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![]() | Approved Vendor to many US, Canada, and EU Universities |
![]() | International Shipping |
![]() | Customer References Available |
![]() | Training and Installation Options Available |
- Stock: In Stock
- Brand: Molecular Devices
- Product Code: 62781
- Condition: Pre-Owned
For Sale Molecular Devices ImageXpress Micro 4 High Content Imaging System
- Fully Functional
- Serviced & in Stock
- Current Model
- Good cosmetic condition
- Technical sales consultation available
- CONTINENTAL US 120 DAYS WARRANTY & 60 DAYS INTERNATIONAL
- Includes remote instrument setup and training session
Here is what you will receive:
- Molecular Devices ImageXpress Micro 4 High Content Imaging System
- Micro 4 Power Supply
- Lumencor Light Engine Sola model
- Single Slide Holder
- Computer running MetaXpress 6.7.2 and MetaXpress PowerCore with license dongles
- Monitor, mouse, keyboard
- Communication and power cables
ImageXpress Micro 4 High Content Imaging System Configuration:
- Camera: Andor Zyla sCMOS camera
- Field of view 10x: 1.97 mm2
- Speed: >200,000 wells/day
- Filter changer: 5-position filter changer
- Installed emission Filters: DAPI, FITC, TRITC, CY5
- Maximum illumination channels: 5
- 4-position objective changer
- Nikon Objectives: Plan APO 4x/0.20, Plan APO Lambda 10x/0.45, Plan Apo 20x/0.75, Plan APO 40x/0.95
- Autofocus: laser+image autofocus
- Plates supported: up to 1536-well plates and Slides with the use of an adapter
- Robotics/Automation-compatible: yes
- Widefield: yes
- 96-well plate scan time, 2 colors, 1 site/well: 2 minutes
Software Modules:
MetaXpress 6.7 Acquisition and Offline Analysis Software included foundational tools:
Time-series acquisition and analysis
Integrated with Acquisition and Analysis Wizards
Z-series acquisition
Acquisition integrated with the Acquisition Wizard
Z-series analysis
Analysis integrated into the workflow
Compatible with MetaXpress PowerCore software
Customized analysis
Integrated Custom Module Editor
Transmitted light segmentation
Simple step cards are available with the Custom Module Editor
Asynchronous kinetics
Built into the Acquisition Wizard
Basic curve fitting
Included with the MetaXpress software
Peak analysis
Included with the MetaXpress software
Basic 3D acquisition setup tools
Includes Z-stack capture, 2D projection options
Interactive GUI for Z settings
Note: As shown in the modules below, this system includes the standard software package and does not include add-on modules.
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Customization/Options:
- Other objectives may be available; please inquire with our sales team.
Testing performed by our in-house service team:
The ImageXpress Micro 4 High Content Imaging System passed all tests and was found to be fully functional:
- We initialized the ImageXpress Micro 4 System.
- We established communication with the software.
- We checked the clarity of the objectives.
- We tested the laser autofocus functionality.
- We ensured clarity in all installed filters.
- We verified the functionality of the Lumencor Sola
- We performed multi-well acquisitions.
- We performed multi-channel slide acquisitions with image stitching.
- We tested the filter slider functionality.
- We conducted spatial calibration.
- We confirmed camera clarity and functionality.
- We verified full X and Y stage movement.
- We confirmed the full Z movement.
Instrument Overview:
- Advanced imaging platform designed for automated high-content microscopy of multiwell plates and slides.
- Features a high-sensitivity sCMOS camera providing a large field of view and fast image acquisition.
- Compatible with various plate formats up to 1536 wells and slide imaging for flexible experiment setups.
- Offers multiple objective options for a wide range of magnifications and imaging resolutions.
- Supports multicolor imaging with interchangeable optical filters and stable illumination sources.
- The ImageXpress Micro 4 enables rapid, reliable data collection for high-throughput imaging workflows.
Instrument Application:
- Cell viability and cytotoxicity assays
- Phenotypic screening of compounds
- 3D spheroid and organoid imaging
- Cell migration and wound healing studies
- Quantification of protein expression or localization
The Key Features:
- High-speed automated imaging system
- Supports plates and slide samples
- sCMOS camera for sharp imaging
- Multiple fluorescence filter options
- Laser and image-based autofocus
- Compatible with lab automation tools
Additional technical info:
- Pre-installation Guide: ImageXpress Micro 4 High Content Imaging System Pre-installation Guide
- Manual: ImageXpress Micro 4 High Content Imaging System Manual
Video Overview:
About us

How we pack

VIEW SOME OF THE CUSTOMERS WE HELPED HERE
WHY DO CUSTOMERS MAKING CRITICAL LAB PURCHASES CHOOSE TO ORDER IMAGING SYSTEMS FROM US?
They want to ensure that internal optics are properly cleaned.
They want to ensure that internal mechanical and motorized mechanisms are lubricated and aligned.
They want to ensure that image quality is verified at the sample point for field distortion and uniformity.
They want assurance that the motorized sample stage is responsive and accurately positions microplates and slides for repeatable image capture, avoiding well misalignment or incomplete scan coverage.
They want to confirm excitation sources (LED, laser, or arc lamp) have been tested for power stability and wavelength accuracy, ensuring consistent fluorescence signal intensity across experiments.
They want to ensure both brightfield and fluorescence imaging modes produce uniform, high-contrast, artifact-free images, verified through multi-mode scans and visual QC overlays.
They want peace of mind, knowing their instrument is backed by a warranty from a company that can stand behind it.

- We have experience servicing and repairing these instruments.
- This instrument goes through all the described service steps before shipping. see the questions section below
- We offer detailed photos and videos of the instruments you buy.
- We are an approved pre-owned equipment vendor to many large US, Canadian, and EU Universities.
- We are an approved pre-owned equipment vendor to many Fortune 500 US and International Biopharma companies.
- Technical sales consultation available
- Remote installation and instrument operation training may be available.
- On-site installation may be available in the Boston Area (New England area)
- US or International shipping is no problem (see the shipping tab on how we pack and feel at ease)

- Warranty
- You get after-sales technical support
- Customer references are available
- The instrument will be fully functional!
- Smooth process from the initial quote to order fulfillment
This will ship via freight. Please contact us with your zip code to obtain a shipping quote.
*LA* Large Crate
725#
COMMON QUESTIONS AND ANSWERS BELOW
What are the steps you take to verify, service, and confirm the functionality of the ImageXpress Micro 4 High Content Imaging System?
We verify various instrument functions individually and together, performing necessary repairs or maintenance to bring the instrument to our quality standards..
- We initialized the ImageXpress Micro 4 System.
- We established communication with the software.
- We checked the clarity of the objectives.
- We tested the laser autofocus functionality.
- We ensured clarity in all installed filters.
- We verified the functionality of the Lumencor Sola
- We performed multi-well acquisitions.
- We performed multi-channel slide acquisitions with image stitching.
- We tested the filter slider functionality.
- We conducted spatial calibration.
- We confirmed camera clarity and functionality.
- We verified full X and Y stage movement.
- We confirmed the full Z movement.
What supplies do I need?
You will need the consumables starting out:
Can I view the ImageXpress Micro 4 High Content Imaging System in person at your facility or do a live Zoom demo before it is shipped to me?
We invite you to visit our facility for an on-site demo or feel free to request a virtual Zoom demo of the instrument you are interested in.
What about the warranty? Installation, training, maintenance?
Warranty Terms:
- The instrument comes fully warranted for both parts and labor.
- The customer should retain all packing materials during the warranty period.
What should I watch out for when buying an ImageXpress Micro 4 High Content Imaging System used/pre-owned from another lab?
- Make sure the instrument is properly packed for shipping and will arrive safely. If the instrument is large, request to have it packed in a wooden crate.
- Confirm that there is no physical damage or any misaligned internal components.
- Ask what accessories are included.
- Ask how long the warranty is and what it covers.
Here is what our technical team tests so you can request something similar and ensure your instrument will be fully functional.
- We initialized the ImageXpress Micro 4 System.
- We established communication with the software.
- We checked the clarity of the objectives.
- We tested the laser autofocus functionality.
- We ensured clarity in all installed filters.
- We verified the functionality of the Lumencor Sola
- We performed multi-well acquisitions.
- We performed multi-channel slide acquisitions with image stitching.
- We tested the filter slider functionality.
- We conducted spatial calibration.
- We confirmed camera clarity and functionality.
- We verified full X and Y stage movement.
- We confirmed the full Z movement.
We recommend inspecting the instrument in person or requesting a virtual demo; this will allow you to evaluate the condition and performance of the instrument you are considering purchasing.
Do you have an ImageXpress Micro 4 High Content Imaging System on hand?
- This is a common model, and we generally stock multiple instruments, accessories, and many replacement parts to back up our warranty.
I found it elsewhere for less. What goes into your price?
We acknowledge that sometimes you can purchase this model instrument elsewhere, possibly for less.
Here are some of the reasons for our price.
- We may offer longer warranty terms.
- We cover shipping costs during the warranty period. (Customer is required to save packing materials for the duration).
- We have to have technical staff that can do the testing/repairs and after-sales support if there are any issues.
- We invest considerable time into the testing and service of each instrument we sell.
- We have to purchase various testing supplies (often expensive) to perform testing.
- We have to purchase any missing required accessories to make the instruments complete.
- We have to procure and stock service parts to support our warranty.
- We have extensive experience packing sensitive instruments. See the shipping section in the website menu for info on how not to pack.
- We guarantee that the instrument will be functional.
This procurement is for a University or College. Are purchase orders with NET terms accepted?
- If you are a US or Canadian customer, we are likely already a registered vendor in your University's vendor system. This would greatly expedite the process of PO approvals and get this instrument into your lab faster.
- POs are accepted from US and Canadian universities.
How fast will you ship?
- We can ship within a few days to two weeks. Shipping time depends on the current demand for our instruments. Members of our sales team will be able to offer current delivery estimates.
Will my instrument be insured during shipping?
- All instruments shipped within the USA and internationally are fully insured. This applies as long as we are the shipper and handle shipping arrangements.
- If the buyer handles shipping, then shipping insurance responsibility falls to the buyer; we highly advise that the buyer obtain shipping insurance from their carrier.
How do you pack? Have you packed and shipped ImageXpress Micro 4 High Content Imaging System Instruments in the past? Do you ship Internationally?
Packing
- Most larger instruments ship in fully enclosed ISPM15-certified wooden crates with proper padding underneath, and the sides have moving components braced.
- Accessories are packed safely in boxes with padding and then safely packed inside the crate.
- We may not use a crate for local deliveries to save you money *if delivered by us.
- We often use “tilt’ & “shock” indicators on the crates to ensure the crate has not been excessively tilted and dropped where equipment may suffer damage.
- Photos are taken during the packing process to make sure nothing is missed.
USA/Canada Shipping
- Within the US and Canada, we will ship via selected freight carriers. We do not use low-price/high-damage carriers as we want the equipment to get safely to you.
International Shipping
- Internationally, we will only ship via Air Freight or Air Parcel (such as UPS or DHL), which provides reliability, no exposure to Ocean weather, and timely delivery.
We have extensive experience packing and shipping fragile instruments globally.
Our experience and process
- We have safely packed and shipped thousands of sensitive analytical instruments.
How much will I save buying it pre-owned, and is it worth it?
A lot…and it is undoubtedly worth it, and here is why. Feel free to ask for feedback from hundreds of customers who bought from us.
- You will pay less than half vs. buying a new instrument. Why not spend leftover funds on another instrument for your lab?
- You will get our standard warranty, plus, when available, an option to obtain an extended warranty agreement.
- Know that your instrument was tested and working the day it left our facility and is covered if there are faults.
- Get extra peace of mind by adding an extended warranty or service agreement when such an option is available.
Sustainability
- Well, this one is easy: buying a pre-owned instrument is great for the planet; you are reducing unnecessary waste, CO2 output, and water use that would be used during the manufacturing process.
I have more questions; I want to receive a formal quote.
Absolutely! Please give us a call (1-617-397-3486) or complete this form to get your questions answered or receive a formal Quote.
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