Laboratory

Detection technology: Bio-Layer Interferometry (BLI)
16 spectrometers with up to 16 simultaneous reads
Molecular weight: >150 Da
Sample volume: 40-220 uL (depending on plate type)
Microplate positions: 96- and 384-well microplates, two plate positions

Robotic Arms: Span-8 w/ Gripper, 96-Multichannel Arm w/ Gripper
Channels: 8, 96
Volume: 1-1000 on Span-8, 5-1070 on 96-Multichannel
Disposable Tips: P20, P30, P30XL, P250, P1000 (P1000 for span 8 only)
Application: liquid handling and sample preparation

(5) Lasers: Blue 488 nm (200mW) / Red 640 nm (140mW) / Violet 405 nm (200mW) / UV 355 nm (109mW) / Yellow-Green 561 nm (150mW)
Laser Color Allocation (Laser/Channel Count): 6-Blue, 3-Red, 7-Violet, 5-Yellow/Green, 8-UV
Acquisition rate: 40,000 events/second with beads
Fluorescence resolution: (CV) PI: Area, <3.0%, full G^0 /G^1 peak for PI-stained CEN
Sample Handling: HTS High Throughput Sampler

5 lasers, 30 colors, 32 detectors with solid‑state design
SiPM detection, FSC sensitivity 0.4 um, SSC 0.1 um
Fluorescence sensitivity: FITC ≤40 MESF, PE ≤10 MESF
100,000 events/sec with syringe‑pump volumetric counting
NovoSampler Q supports tubes and multi‑well plates

Robotic Arm(s): Flexible Channel Arm with (Span-8 FCA), Multi-Channel Arm (MCA), RGA Gripper Arm
Pipetting Channel(s): 8 (FCA) and 96 (MCA)
Pipetting Volume: 0.5 to 1000uL
Tips: Disposable Tips 10, 50, 200, 350, 1000uL can be mounted
Application: liquid handling and sample preparation

Robotic Arm(s): Flexible Channel Arm with Air System (Span-8 FCA), Multi-Channel Arm (MCA), Robotic Gripper Arm (RGA)
Pipetting Channel(s): 8 (FCA) and 96 (MCA)
Pipetting Volume: 0.5 to 1000uL
Tips: Disposable Tips 10, 50, 200, 350, 1000uL can be mounted
Application: liquid handling and sample preparation

Parallel bioreactors: (6x) Biostat B-DCU Univessel SU stations with central DCU tower
Gas control: Advanced Additive Flow 4-gas module with 6 TMFCs and sparger/overlay routing
Agitation range with direct drive: 20-2000 rpm (vessel dependent)
Pumping: Integrated peristaltic pumps for Base, Substrate A & B with gravimetric scale support
Temperature control: 220W heating blankets

Parallel System: 6 bioreactor stations with 6x2L vessels
Gas Control: 4 TMFCs (Thermal Mass Flow Controller), Precision: ±0.3% full scale
Agitation: Direct-drive motors, 20–2000 rpm
Temperature Regulation: external heating blanket and cooling finger with a range from 8 °C above coolant to 60 °C.
Fluid Handling: 4 Watson Marlow 114, fixed speed pumps Base, Acid (5 rpm); Subs-A, Subs-B (44 rpm); rotary switch-controlled.

Andor Zyla sCMOS camera with dual-disk spinning confocal optics (50 µm slit, 60 µm pinhole)
Laser and image-based autofocus with encoded XYZ stages offering <25 nm positioning resolution
Automated objective changer with 4×, 10×, 20× water, and 40× water immersion objectives
Supports slides and 1–1536 well plates; throughput >160K wells/day confocal imaging
Environmental control, water immersion, and transmitted light imaging modules

Optofluidic single-cell manipulation platform
OEP-based light-directed cell positioning
500 pL-1 nL NanoPen chamber volumes
Five filter cubes: 4 for fluorescence and 1 for brightfield/OEP
Per-chip temperature regulation (10–40DegC)

Orientation: Inverted
Illumination Type: Brightfield, Fluorescence
Objectives: Nikon Plan Apo λ 10x/0.45, Nikon S Fluor 20x/0.75, Nikon Apo 60x/1.40 Oil λS
Light Sources: LED Brightfield lamp, Lumencor SOLA, LU-N3-SIM laser unit
Stage: Motorized XY

Capable Studies: Widefield, Brightfield, Confocal
Wavelength range: 7 class 3B lasers (405 nm/100 mW; 450 nm/75 mW; 488 nm/120 mW; 561 nm/100 mW; 594 nm/100 mW; 647 nm/120 mW; 785 nm/100 mW)
Microplate Types: clear bottom 96-, 384- and 1536-, slides as well with insert adapter (up to 4 glass microscope slides)
Objectives: 10x/0.40 UPlanXApo, 20x/0.45 LUCPlanFL N, 40x/0.60 LUCPlanFL N (3 position objective changer)
Focus resolution: Sub-micron step size with advanced micro-stepping and double-stepping capabilities 

Optics:(4) Lasers, (14) Colors, (16) Detectors
405nm violet laser: 6 Flr channels; 488nm blue laser: 2 Flr channels; 561nm yellow laser: 3 Flr channels; 637nm red laser: 3 Flr channels;
Flow Rate: 12.5 to 1,000 uL/min
Sample Analysis Volume: 20ul - 4mL
Particle Size Range: 0.5 - 50um

Optofluidic single-cell manipulation platform
OEP-based light-directed cell positioning
500 pL-1 nL NanoPen chamber volumes
Five filter cubes: 4 for fluorescence and 1 for brightfield/OEP
Per-chip temperature regulation (10–40DegC)

Membrane Width: 5 mm - 120 mm; speed adjustable up to 100 mm/sec
(7) Dispensers: (4) BioJet (solenoid valve) and (3) AirJet (pneumatic) dispensers with tandem pumps
Dual drying towers, each with 3 IR-heated zones and real-time temperature feedback
Keyence CA-H048MX (2448×2048 px) camera with CA-LH8 (8 mm, f/1.4) lens for in-line vision inspection
Capstan-driven tension control, diptank module with level sensing, and automated marking system

8 independently controlled single-use bioreactor stations
100–250 mL working volume per vessel
Agitation range 100–4500 rpm; 18–55°C ±0.5°C
pH 2.0–8.5 (±0.02); DO 0–200% air saturation
5 syringe pumps + 1 peristaltic pump per vessel

Robotic Arms: Span-8 w/ Gripper, 96-Multichannel Arm w/ Gripper
Channels: 8, 96
Volume: 1-1000 on Span-8, 5-1070 on 96-Multichannel
Disposable Tips: P20, P30, P30XL, P250, P1000 (P1000 for span 8 only)
Application: liquid handling and sample preparation

Robotic Arms: Span-8 w/ Gripper, 384-Multichannel Arm w/ Gripper
Channels: 8, 384
Volume: 1-1000 on Span-8, 0.5-60 ul on 384-Multichannel
Disposable Tips: 25, 40ul (Filtered) 30, 50ul (Non-Filtered) disposable tips for 384-MCA; P20, P30, P30XL, P250, P1000 for span-8
Application: liquid handling and sample preparation

5 lasers, 30 colors, 32 detectors with solid‑state design
SiPM detection, FSC sensitivity 0.4 um, SSC 0.1 um
Fluorescence sensitivity: FITC ≤40 MESF, PE ≤10 MESF
100,000 events/sec with syringe‑pump volumetric counting
NovoSampler Q supports tubes and multi‑well plates

(5) Lasers: Blue 488 nm (200mW) / Red 628 nm (200mW) / Violet 405 nm (200mW) / UV 355 nm (60mW) / Yellow-Green 552 nm (200mW)
Laser Color Allocation (Laser/Channel Count): 6-Blue, 3-Red, 8-Violet, 5-Yellow/Green, 7-UV
Acquisition rate: 40,000 events/second with beads
Fluorescence resolution: (CV) PI: Area, <3.0%, full G^0 /G^1 peak for PI-stained CEN
Sample Handling: HTS High Throughput Sampler

(5) Lasers: Blue 488nm / Red 637nm / Violet 405nm/ UV 355nm/ Yellow Green 561nm
Laser Color Allocation: 4-Blue, 3-Red, 6-Violet, 4-Yellow/Green, 6-UV
Acquisition rate: 40,000 events/second with bead
Fluorescence resolution: (CV) PI: Area, <3.0%, full G^0 /G^1 peak for PI-stained CEN
Sample Handling: HTS High Throughput Sampler

(5) Lasers: Blue 488nm / Red 637nm / Violet 405nm/ UV 355nm/ Yellow Green 561nm
Laser Color Allocation: 3-Blue, 3-Red, 6-Violet, 4-Yellow/Green, 6-UV
Acquisition rate: 40,000 events/second with bead
Fluorescence resolution: (CV) PI: Area, <3.0%, full G^0 /G^1 peak for PI-stained CEN
Sample Handling: HTS High Throughput Sampler

4 x 7.5 L double-walled vessels
High-torque servomotor, 20–1500 rpm stirring
4 Mass Flow Controllers for Air, O₂, N₂, CO₂
4 built-in + 1 external peristaltic pumps
Digital pH & DO sensors

4 x 7.5 L double-walled vessels
High-torque servomotor, 20–1500 rpm stirring
4 Mass Flow Controllers for Air, O₂, N₂, CO₂
4 built-in + 1 external peristaltic pumps
Digital pH & DO sensors

Excitation lasers: Violet (405 nm), Blue (488 nm), Yellow-green (561 nm), Far red (640 nm)
Laser/Channel Count: 7V-7B-7Y-4R; Scatter parameters: standard FSC and SSC 488 nm
Nozzle: 100 um ceramic nozzle, 30 PSI
Sample input tube types: 1.5 mL, 5 mL, and 15 mL
Temperature control: 4 DegC-37 DegC for input and output of all media types