Biochemistry Analyzers

Selecting the right bioreactor depends on your application requirements, culture type, process scale, and level of environmental control needed.

• Culture Type – Mammalian cell culture and microbial fermentation often require different vessel designs, agitation methods, and oxygen transfer capabilities
• Working Volume and Scale – Consider vessel size and scalability, from benchtop R&D systems to pilot-scale production platforms
• Control Parameters – Evaluate control capabilities for temperature, pH, dissolved oxygen (DO), agitation, and gas flow
• Single-Use vs. Stainless Steel Systems – Single-use systems reduce cleaning requirements, while stainless steel platforms support long-term reuse and scalability
• Agitation and Mixing Performance – Proper mixing and shear control are critical for maintaining healthy cell cultures and efficient fermentation
• Automation and Software – Advanced control software can improve monitoring, data logging, and process reproducibility
• Gas Exchange and Aeration – Oxygen transfer and gas control are essential for maintaining optimal biological growth conditions
• Sterility and Cleaning Requirements – Consider sterilization methods, SIP/CIP capabilities, and contamination control requirements
• Expandability and Integration – Some systems support integration with additional sensors, feeding systems, and downstream process equipment
• System Condition and Service History – Proper testing and servicing are important for helping ensure the reliable operation of pre-owned systems

Biochemistry analyzers support a wide range of biotechnology, pharmaceutical, and life science workflows involving metabolite measurement, protein characterization, and cell culture monitoring.

• Cell Culture Monitoring – Measurement of glucose, lactate, ammonia, osmolality, cell density, and viability in bioprocess workflows
• Bioprocess Development – Monitoring and optimization of culture conditions during upstream process development
• Protein Stability Analysis – Evaluation of protein aggregation, unfolding, and thermal stability during formulation and development
• Binding Kinetics and Affinity Studies – Characterization of biomolecular interactions using technologies such as SPR and BLI
• Metabolite Analysis – Quantification of nutrients and metabolic byproducts in fermentation and cell culture applications
• Biologics Development – Analysis and characterization of proteins, antibodies, and therapeutic biomolecules
• Fermentation Monitoring – Real-time assessment of microbial growth conditions and metabolite consumption
• Cell Therapy Research – Monitoring culture health and process conditions for cell-based therapeutic development
• Quality Control and Process Monitoring – Support for reproducibility and consistency in biopharmaceutical workflows
• Academic and Industrial Research – General biochemical and protein analysis across research laboratories and production environments