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Unchained Labs Uncle Protein Stability Analyzer, Made in 2024 Unit 3

Unchained Labs Uncle Protein Stability Analyzer, Made in 2024 Unit 3
Unchained Labs Uncle Protein Stability Analyzer, Made in 2024 Unit 3
Unchained Labs Uncle Protein Stability Analyzer, Made in 2024 Unit 3
Unchained Labs Uncle Protein Stability Analyzer, Made in 2024 Unit 3
Unchained Labs Uncle Protein Stability Analyzer, Made in 2024 Unit 3
Unchained Labs Uncle Protein Stability Analyzer, Made in 2024 Unit 3
Unchained Labs Uncle Protein Stability Analyzer, Made in 2024 Unit 3
Unchained Labs Uncle Protein Stability Analyzer, Made in 2024 Unit 3
Unchained Labs Uncle Protein Stability Analyzer, Made in 2024 Unit 3
Unchained Labs Uncle Protein Stability Analyzer, Made in 2024 Unit 3
Unchained Labs Uncle Protein Stability Analyzer, Made in 2024 Unit 3
Unchained Labs Uncle Protein Stability Analyzer, Made in 2024 Unit 3
Unchained Labs Uncle Protein Stability Analyzer, Made in 2024 Unit 3
Unchained Labs Uncle Protein Stability Analyzer, Made in 2024 Unit 3
Unchained Labs Uncle Protein Stability Analyzer, Made in 2024 Unit 3
Unchained Labs Uncle Protein Stability Analyzer, Made in 2024 Unit 3
Unchained Labs Uncle Protein Stability Analyzer, Made in 2024 Unit 3
Unchained Labs Uncle Protein Stability Analyzer, Made in 2024 Unit 3
Unchained Labs Uncle Protein Stability Analyzer, Made in 2024 Unit 3
Unchained Labs Uncle Protein Stability Analyzer, Made in 2024 Unit 3
Unchained Labs Uncle Protein Stability Analyzer, Made in 2024 Unit 3
Unchained Labs Uncle Protein Stability Analyzer, Made in 2024 Unit 3
Unchained Labs Uncle Protein Stability Analyzer, Made in 2024 Unit 3
Unchained Labs Uncle Protein Stability Analyzer, Made in 2024 Unit 3
Unchained Labs Uncle Protein Stability Analyzer, Made in 2024 Unit 3
Approved Vendor to many US, Canada, and EU Universities
International Shipping
Customer References Available 
Training and Installation Options Available

 

  • Stock: In Stock
  • Brand: Unchained Labs
  • Product Code: 65051
  • Condition: Pre-Owned
$32,995.00
CLICKABLE TABS BELOW

For Sale Unchained Labs Uncle Protein Stability Analyzer Unit 3

 

  • Fully Functional
  • Serviced & in Stock
  • Current Model
  • Made in 2024
  • Good cosmetic condition
  • Technical sales consultation available
  • CONTINENTAL US 120 DAYS WARRANTY & 60 DAYS INTERNATIONAL
  • Includes remote instrument setup and training session

 


Here is what you will receive:

  • Unchained Labs Uncle Protein Stability Analyzer
  • Standard power cord

 

Uncle Protein Stability Analyzer Configuration:

Techniques: Full-spectrum Fluorescence, Static Light Scattering (SLS), Dynamic Light Scattering (DLS)

Sample Requirements:

  • Minimum sample volume: 9 uL (sealed capillaries)

  • Simultaneous samples per run: 48

  • Sample concentration range: 0.05–300 mg/mL (IgG, protein dependent)

Temperature Control:

  • Range: 15–95 DegC
  • Accuracy: ±0.1 DegC
  • Heating rate: 0.1–10 DegC/minute

Fluorescence and static light scattering:

  • Sample precision: <2% CV (Tm)
  • SLS resolution: ~15 kDa change in mean molecular mass
  • AAV genome concentration: ≥5 x 1011 viral genomes per mL
  • Excitation: 266 nm and 473 nm lasers
  • Detection Fluorescence: CCD spectrometer at full 250–720 nm spectral range
  • SLS: intensity at 266 nm and 473 nm

Dynamic light scattering:

  • Hydrodynamic diameter range: 0.3–1000 nm
  • Size accuracy: ±2%
  • Minimum sample concentration: 0.1 mg/mL — lysozyme
  • AAV capsid concentration: ≥5 x 1011 viral genomes per mL
  • Molecular weight range: 192 Da – 25 MDa
  • Light source: 660 nm laser diode
  • Detection: avalanche photodiode module

 

Customization/Options: N/A

 

Testing performed by our in-house service team: 

  • We power on the system and confirm successful initialization.
  • We clean and inspect the unit for any signs of wear or damage.
  • We test and verify the connection to the control software.
  • We prepare a protein sample and load it into a “Uni” for testing runs.
  • We test Thermal melting (Tm) during the run.
  • We test Thermal aggregation (Tagg) during the run.
  • We test Sizing and Polydispersity using DLS capability.

 

Instrument Overview:

  • Uncle combines fluorescence, SLS, and DLS to analyze stability with minimal sample volume.
  • Measures Tm, Tagg, size, polydispersity, and viscosity using 9 uL samples in sealed capillaries.
  • Supports 48 samples per run with temperature control from 15–95 DegC and heating rates up to 10 DegC/min
  • Features excitation at 266 and 473 nm with full-spectrum fluorescence detection from 250–720 nm
  • The Unchained Labs Uncle detects aggregation and hydrodynamic diameter from 0.3 to 1000 nm.
  • Compact and efficient, the Uncle Protein Stability Analyzer offers high-throughput biophysical profiling.

 

Instrument Application:

  • Tm & Tagg
  • Tm with SYPRO (DSF)
  • Isothermal stability studies
  • Sizing & polydispersity
  • Sizing with thermal ramp
  • Viscosity, kD, B22, G22, ΔG
  • Thermal recovery

 

The Key Features:

  • Measures Tm, Tagg, and particle sizing
  • Uses only 9 uL per sample
  • Combines 3 technologies in one unit
  • Supports high-throughput screening
  • Works with proteins, biologics, and more
  • Fast analysis with intuitive software

 

Video Overview:

 

About us

 

How we pack

  



 VIEW SOME OF THE CUSTOMERS WE HELPED HERE 

  

  • We have experience servicing and repairing these instruments.
  • This instrument goes through all the described service steps before shipping. see the questions section below
  • We offer detailed photos and videos of the instruments you buy.
  • We are an approved pre-owned equipment vendor to many large US, Canadian, and EU Universities.
  • We are an approved pre-owned equipment vendor to many Fortune 500 US and International Biopharma companies.
  • Technical sales consultation available
  • Remote installation and instrument operation training may be available.
  • On-site installation may be available in the Boston Area (New England area)
  • US or International shipping is no problem (see the shipping tab on how we pack and feel at ease)

 


  • Warranty
  • An extended warranty may be available
  • You get after-sales technical support
  • Customer references are available
  • The instrument will be fully functional!
  • Smooth process from the initial quote to order fulfillment

 


This will ship via freight. Please contact us with your zip code to obtain a shipping quote.

 

COMMON QUESTIONS AND ANSWERS BELOW

 

What are the steps you take to verify, service, and confirm the functionality of the Uncle Protein Stability Analyzer?

We verify various instrument functions individually and together, performing necessary repairs or maintenance to bring the instrument to our quality standards..

  • We power on the system and confirm successful initialization.
  • We clean and inspect the unit for any signs of wear or damage.
  • We test and verify the connection to the control software.
  • We prepare a protein sample that is loaded into a “Uni” for the testing runs.
  • We test Thermal melting (Tm) during the run.
  • We test Thermal aggregation (Tagg) during the run.
  • We test Sizing and Polydispersity using DLS capability.

 

Can I view the Uncle Protein Stability Analyzer in person at your facility or do a live Zoom demo before it is shipped to me?

We invite you to visit our facility for an on-site demo or feel free to request a virtual Zoom demo of the instrument you are interested in.

 

What about the warranty? Installation, training, maintenance?

Warranty Terms:

  • The instrument comes fully warranted for both parts and labor.
  • The customer should retain all packing materials during the warranty period.

 

What should I watch out for when buying an Uncle Protein Stability Analyzer used/pre-owned from another lab?
  • Make sure the instrument is properly packed for shipping and will arrive safely. If the instrument is large, request to have it packed in a wooden crate.
  • Confirm that there is no physical damage or any misaligned internal components.
  • Ask what accessories are included.
  • Ask how long the warranty is and what it covers.

 

Here is what our technical team tests so you can request something similar and ensure your instrument will be fully functional.

  • We power on the system and confirm successful initialization.
  • We clean and inspect the unit for any signs of wear or damage.
  • We test and verify the connection to the control software.
  • We prepare a protein sample that is loaded into a “Uni” for the testing runs.
  • We test Thermal melting (Tm) during the run.
  • We test Thermal aggregation (Tagg) during the run.
  • We test Sizing and Polydispersity using DLS capability.

 

We recommend inspecting the instrument in person or requesting a virtual demo; this will allow you to evaluate the condition and performance of the instrument you are considering purchasing.

 

Do you have an Uncle Protein Stability Analyzer on hand?
  • This is a common model, and we generally stock multiple instruments, accessories, and many replacement parts to back up our warranty.

 

I found it elsewhere for less. What goes into your price?

We acknowledge that sometimes you can purchase this model instrument elsewhere, possibly for less.

 

Here are some of the reasons for our price.

  • We may offer longer warranty terms.
  • We cover shipping costs during the warranty period. (Customer is required to save packing materials for the duration).
  • We have to have technical staff that can do the testing/repairs and after-sales support if there are any issues.
  • We invest considerable time into the testing and service of each instrument we sell.
  • We have to purchase various testing supplies (often expensive) to perform testing.
  • We have to purchase any missing required accessories to make the instruments complete.
  • We have to procure and stock service parts to support our warranty.
  • We have extensive experience packing sensitive instruments. See the shipping section in the website menu for info on how not to pack.
  • We guarantee that the instrument will be functional.

 

This procurement is for a University or College. Are purchase orders with NET terms accepted?
  • If you are a US or Canadian customer, we are likely already a registered vendor in your University's vendor system. This would greatly expedite the process of PO approvals and get this instrument into your lab faster.
  • POs are accepted from US and Canadian universities.

 

How fast will you ship?
  • We can ship within a few days to two weeks. Shipping time depends on the current demand for our instruments. Members of our sales team will be able to offer current delivery estimates.

 

Will my instrument be insured during shipping?
  • All instruments shipped within the USA and internationally are fully insured. This applies as long as we are the shipper and handle shipping arrangements.
  • If the buyer handles shipping, then shipping insurance responsibility falls to the buyer; we highly advise that the buyer obtain shipping insurance from their carrier.

 

How do you pack? Have you packed and shipped Uncle Protein Stability Analyzer Instruments in the past? Do you ship Internationally?

Packing

  • Most larger instruments ship in fully enclosed ISPM15-certified wooden crates with proper padding underneath, and the sides have moving components braced.
  • Accessories are packed safely in boxes with padding and then safely packed inside the crate.
  • We may not use a crate for local deliveries to save you money *if delivered by us.
  • We often use “tilt’ & “shock” indicators on the crates to ensure the crate has not been excessively tilted and dropped where equipment may suffer damage.
  • Photos are taken during the packing process to make sure nothing is missed.

USA/Canada Shipping

  • Within the US and Canada, we will ship via selected freight carriers. We do not use low-price/high-damage carriers as we want the equipment to get safely to you.

International Shipping

  • Internationally, we will only ship via Air Freight or Air Parcel (such as UPS or DHL), which provides reliability, no exposure to Ocean weather, and timely delivery.
    We have extensive experience packing and shipping fragile instruments globally.

Our experience and process

  • We have safely packed and shipped thousands of sensitive analytical instruments.

 

How much will I save buying it pre-owned, and is it worth it?

A lot…and it is undoubtedly worth it, and here is why. Feel free to ask for feedback from hundreds of customers who bought from us.

 

  • You will pay less than half vs. buying a new instrument. Why not spend leftover funds on another instrument for your lab?
  • You will get our standard warranty, plus, when available, an option to obtain an extended warranty agreement.
  • Know that your instrument was tested and working the day it left our facility and is covered if there are faults.
  • Get extra peace of mind by adding an extended warranty or service agreement when such an option is available.

 

Sustainability
  • Well, this one is easy: buying a pre-owned instrument is great for the planet; you are reducing unnecessary waste, CO2 output, and water use that would be used during the manufacturing process.

 

I have more questions; I want to receive a formal quote.

Absolutely! Please give us a call (1-617-397-3486) or complete this form to get your questions answered or receive a formal Quote.