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Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System

Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System
Approved Vendor to many US, Canada, and EU Universities
International Shipping
Customer References Available 
Training and Installation Options Available

 

  • Stock: In Stock
  • Brand: Teledyne Isco
  • Product Code: SM101009-UV
  • Condition: Pre-Owned
$14,995.00
CLICKABLE TABS BELOW

For Sale Teledyne ISCO CombiFlash NextGen 300+ UV Chromatography System

 

  • Fully Functional
  • Serviced & in Stock
  • Current Model
  • Good cosmetic condition
  • Technical sales consultation available
  • CONTINENTAL US 120 DAYS WARRANTY & 60 DAYS INTERNATIONAL
  • Includes remote instrument setup and training session

 


Here is what you will receive:

  • Teledyne Isco CombiFlash NextGen 300+ Chromatography System w/ 12in. LCD display
  • Intake hoses with caps and solvent filters (Qty.:4)
  • Set of waste hoses
  • Power cable

 

CombiFlash NextGen 300+ Chromatography System Configuration:

  • Flow Rate Range: 1–300 mL/min
  • Flow Rate Accuracy: ±5% (5-200 mL/min)
  • Maximum Pressure: up to 20 bar (300 psi); user-defined pressure limits
  • UV Detection: 200 to 400 nm
  • Number of Solvents: binary gradient from 4 solvent inlets
  • Gradient Accuracy: ±2% of full scale
  • Gradient Formation: low pressure
  • Programmable Gradients: linear, step, isocratic
  • Gradient Accuracy: ±2% of full scale
  • Dimensions (H x W x D): 26 x 14.1 x 17 in (66 x 36 x 43 cm)
  • Weight: 61 lb (27.7 kg)
  • Power Requirements: 100-240VAC, 50/60Hz, 2A

 

Customization/Options:

  • We carry a variety of racks, solid load caps, and other accessories. Please inquire with us for availability.

 

Testing performed by our in-house service team:

The CombiFlash NextGen 300+ Chromatography System passed all tests and was found to be fully functional:

  • We verified the power supply and initialization.
  • We calibrated the touch screen interface.
  • We assessed the accuracy of arm movement.
  • We confirmed the RFID column detection.
  • We evaluated the waste and source-level sensing.
  • We clean and inspect the check valves.
  • We tested the manual control functionality.
  • We executed the prime function.
  • We analyzed the gradient performance.
  • We verified the UV detection using a sodium iodide solution.
  • We perform the PHE/N-BBZ test to confirm correct gradient behavior.

 

Instrument Overview:

  • Teledyne ISCO CombiFlash NextGen 300+ Chromatography System is built for reliable flash purification.
  • Supports purification from milligram to multigram scale with consistent results.
  • Precision pump delivers accurate gradients across a broad flow range.
  • Integrated UV detection allows real-time fraction tracking and collection.
  • High-pressure capability enables faster runs with varied stationary phases.
  • Compact footprint conserves bench space while maintaining robust performance.

 

Instrument Application:

  • Purification of organic synthesis reaction products
  • Isolation of natural product extracts into pure fractions
  • Separation of compound libraries in medicinal chemistry
  • Rapid scale-up from small-scale to preparative purification

 

The Key Features:

  • Handles mg to multigram purification loads
  • Single precision pump with gradient control
  • UV detection for real-time fraction collection
  • Pressure rated for faster purification runs
  • Compact system with modular configuration

 

Additional technical info:

 

Video Overview:

 

About us

 

How we pack

  



 VIEW SOME OF THE CUSTOMERS WE HELPED HERE 


WHY DO CUSTOMERS MAKING CRITICAL LAB PURCHASES CHOOSE TO ORDER CHROMATOGRAPHY SYSTEMS FROM US?

 

  They want to ensure all pump heads, seals, and check valves have been tested for consistent pressure generation and stable flow rates, preventing gradient drift, pulsation, or baseline instability.


  They want peace of mind knowing the system has been fully flushed, primed, and run through gradient and collection tests under realistic purification conditions.


  They want to ensure expected retention times for verification standards fall within tolerance, confirming that solvent routing, column integrity, and pump calibration are functioning within manufacturer specifications.


  They want to avoid baseline instability, incorrect solvent mixing, or poor fraction resolution caused by untested pumps, misconfigured detectors, or software timing errors, issues that often go undetected until critical purification work is lost.


  They want assurance that fraction collectors, diverter valves, and switching modules operate correctly under pressure and respond precisely to signal triggers, avoiding miscollection or cross-fraction contamination.


  They want to ensure the UV lamp has been checked for remaining life and replaced if needed, so the system generates good data and is ready to use the same day it is installed.


  They want peace of mind, knowing their instrument is backed by a warranty from a company that can stand behind it.


  • We have experience servicing and repairing these instruments.
  • This instrument goes through all the described service steps before shipping. see the questions section below
  • We offer detailed photos and videos of the instruments you buy.
  • We are an approved pre-owned equipment vendor to many large US, Canadian, and EU Universities.
  • We are an approved pre-owned equipment vendor to many Fortune 500 US and International Biopharma companies.
  • Technical sales consultation available
  • On-site installation may be available in the Boston Area (New England area)
  • US or International shipping is no problem (see the shipping tab on how we pack and feel at ease)

 


  • Warranty
  • You get after-sales technical support
  • Customer references are available
  • The instrument will be fully functional!
  • Smooth process from the initial quote to order fulfillment

 


This will ship via freight. Please contact us with your zip code to obtain a shipping quote.

 

*SM* Small Crate
225#

 

COMMON QUESTIONS AND ANSWERS BELOW

 

What are the steps you take to verify, service, and confirm the functionality of the CombiFlash NextGen 300+ Chromatography System?

We verify various instrument functions individually and together, performing necessary repairs or maintenance to bring the instrument to our quality standards..

  • We verified the power supply and initialization.
  • We calibrated the touch screen interface.
  • We assessed the accuracy of arm movement.
  • We confirmed the RFID column detection.
  • We evaluated the waste and source-level sensing.
  • We clean and inspect the check valves.
  • We tested the manual control functionality.
  • We executed the prime function.
  • We analyzed the gradient performance.
  • We verified the UV detection using a sodium iodide solution.
  • We perform the PHE/N-BBZ test to confirm correct gradient behavior.

 

What supplies do I need?

You will need the consumables starting out:

 

Can I view the CombiFlash NextGen 300+ Chromatography System in person at your facility or do a live Zoom demo before it is shipped to me?

We invite you to visit our facility for an on-site demo or feel free to request a virtual Zoom demo of the instrument you are interested in.

 

What about the warranty? Installation, training, maintenance?

Warranty Terms:

  • The instrument comes fully warranted for both parts and labor.
  • The customer should retain all packing materials during the warranty period.

 

What should I watch out for when buying a CombiFlash NextGen 300+ Chromatography System used/pre-owned from another lab?
  • Make sure the instrument is properly packed for shipping and will arrive safely. If the instrument is large, request to have it packed in a wooden crate.
  • Confirm that there is no physical damage or any misaligned internal components.
  • Ask what accessories are included.
  • Ask how long the warranty is and what it covers.

 

Here is what our technical team tests so you can request something similar and ensure your instrument will be fully functional.

  • We verified the power supply and initialization.
  • We calibrated the touch screen interface.
  • We assessed the accuracy of arm movement.
  • We confirmed the RFID column detection.
  • We evaluated the waste and source-level sensing.
  • We clean and inspect the check valves.
  • We tested the manual control functionality.
  • We executed the prime function.
  • We analyzed the gradient performance.
  • We verified the UV detection using a sodium iodide solution.
  • We perform the PHE/N-BBZ test to confirm correct gradient behavior.

 

We recommend inspecting the instrument in person or requesting a virtual demo; this will allow you to evaluate the condition and performance of the instrument you are considering purchasing.

 

Do you have a CombiFlash NextGen 300+ Chromatography System on hand?
  • This is a common model, and we generally stock multiple instruments, accessories, and many replacement parts to back up our warranty.

 

I found it elsewhere for less. What goes into your price?

We acknowledge that sometimes you can purchase this model instrument elsewhere, possibly for less.

 

Here are some of the reasons for our price.

  • We may offer longer warranty terms.
  • We cover shipping costs during the warranty period. (Customer is required to save packing materials for the duration).
  • We have to have technical staff that can do the testing/repairs and after-sales support if there are any issues.
  • We invest considerable time into the testing and service of each instrument we sell.
  • We have to purchase various testing supplies (often expensive) to perform testing.
  • We have to purchase any missing required accessories to make the instruments complete.
  • We have to procure and stock service parts to support our warranty.
  • We have extensive experience packing sensitive instruments. See the shipping section in the website menu for info on how not to pack.
  • We guarantee that the instrument will be functional.

 

This procurement is for a University or College. Are purchase orders with NET terms accepted?
  • If you are a US or Canadian customer, we are likely already a registered vendor in your University's vendor system. This would greatly expedite the process of PO approvals and get this instrument into your lab faster.
  • POs are accepted from US and Canadian universities.

 

How fast will you ship?
  • We can ship within a few days to two weeks. Shipping time depends on the current demand for our instruments. Members of our sales team will be able to offer current delivery estimates.

 

Will my instrument be insured during shipping?
  • All instruments shipped within the USA and internationally are fully insured. This applies as long as we are the shipper and handle shipping arrangements.
  • If the buyer handles shipping, then shipping insurance responsibility falls to the buyer; we highly advise that the buyer obtain shipping insurance from their carrier.

 

How do you pack? Have you packed and shipped CombiFlash NextGen 300+ Chromatography System Instruments in the past? Do you ship Internationally?

Packing

  • Most larger instruments ship in fully enclosed ISPM15-certified wooden crates with proper padding underneath, and the sides have moving components braced.
  • Accessories are packed safely in boxes with padding and then safely packed inside the crate.
  • We may not use a crate for local deliveries to save you money *if delivered by us.
  • We often use “tilt’ & “shock” indicators on the crates to ensure the crate has not been excessively tilted and dropped where equipment may suffer damage.
  • Photos are taken during the packing process to make sure nothing is missed.

USA/Canada Shipping

  • Within the US and Canada, we will ship via selected freight carriers. We do not use low-price/high-damage carriers as we want the equipment to get safely to you.

International Shipping

  • Internationally, we will only ship via Air Freight or Air Parcel (such as UPS or DHL), which provides reliability, no exposure to Ocean weather, and timely delivery.
    We have extensive experience packing and shipping fragile instruments globally.

Our experience and process

  • We have safely packed and shipped thousands of sensitive analytical instruments.

 

How much will I save buying it pre-owned, and is it worth it?

A lot…and it is undoubtedly worth it, and here is why. Feel free to ask for feedback from hundreds of customers who bought from us.

 

  • You will pay less than half vs. buying a new instrument. Why not spend leftover funds on another instrument for your lab?
  • You will get our standard warranty, plus, when available, an option to obtain an extended warranty agreement.
  • Know that your instrument was tested and working the day it left our facility and is covered if there are faults.
  • Get extra peace of mind by adding an extended warranty or service agreement when such an option is available.

 

Sustainability
  • Well, this one is easy: buying a pre-owned instrument is great for the planet; you are reducing unnecessary waste, CO2 output, and water use that would be used during the manufacturing process.

 

I have more questions; I want to receive a formal quote.

Absolutely! Please give us a call (1-617-397-3486) or complete this form to get your questions answered or receive a formal Quote.