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Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage

Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage
Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage

Approved Vendor to many US, Canada, and EU Universities

US & International Shipping

Hundreds of Custom Microscopes  Shipped
Customer References Available 
Training and Installation Options Available

 

  • Stock: In Stock
  • Brand: Nikon
  • Product Code: 47426
  • Condition: Pre-Owned
$37,995.00

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For Sale Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285, HEKA EPC 10 Patch Clamp, Faraday Cage

 

  • Fully Functional
  • Serviced & in Stock
  •  Customized to your requirements
  •  Includes new fluorescence filters
  •  Technical sales consultation available
  •  Continental USA 120 DAYS WARRANTY & 60 DAYS INTERNATIONAL
  •  Includes remote microscope training session and software overview
  • More info about our Microscopy Capabilities or view the Microscope Buying Guide

 

 

Please note the whole electrophysiology setup is currently installed on the Nikon Eclipse TI-S Inverted Microscope. Should you prefer a different inverted microscope, we can swap to the following microscopes:

  • Nikon: Ti-U, Current Model Nikon Ti2-U
  • Zeiss: Axio Observer
  • Olympus: IX70, IX71, IX73 (if available)

 

As configured setup for Patch Clamp Electrophysiology with DIC studies

 

Installed electrophysiology accessories

  • This setup includes a Sutter MP-285 micromanipulation setup (controller, stage/holder and joystick)
  • HEKA 10 USB Digital amplifier with the headstage allowing for recording using Heka Patch Master software, license dongle included
  • The XY mechanical stage has a travel range of 70 x 50mm. It will allow for observation of prepared slides and petri dishes.
  • Included Faraday cage is an enclosure that is used to protect the contained objects from both static and non-static electromagnetic fields
  • The included TMC Anti-Vibration features TMC's Gimbal Piston Air Isolators, which allow quick dissipation of disturbances on the isolated tabletop and clear imaging without interference from local vibration around the lab.
  • Enhancing components, such as Fluorescence Filter Cubes, have been added (Other components are available)
  • The total current magnification range of this microscope is 40 to 200x (Other objectives are available)

 

Please note all the above microscopes are fully mechanical to eliminate electromagnetic interference.

Either configuration can be set up with fluorescence (DIC on Zeiss is subject to availability)

 

This is what you will receive before customizing this microscope:

Standard Nikon Ti-S Microscope Configuration: 

 

Microscopy Techniques:

Brightfield with DIC, Fluorescence Microscopy and Patch Clamp Electrophysiology

 

Base:

  • Nikon Eclipse Ti-S Inverted Microscope
  • Faraday Cage
  • TMC Anti-Vibration Table

Head:

  • Ti-TS B Binocular Head
  • (2) CFI 10x/22 Eyepieces

Condenser:

  • LWD 0.52 Condenser
  • DIC NI Condenser Insert

Brightfield Path:

  • TI-DH Illumination Arm

Fluorescence Path:

  • TI-FL-EPI path

Fluorescence filter cube turret:

  • 6-position Motorized Turret

Fluorescence Filter Cubes:

  • Three empty filter cubes
  • Three Brand New filter sets of either DAPI, FITC, Texas Red or CY3

*Other filters available - please inquire*
Fluorescence Illumination:

  • EXFO X-Cite 120 Metal Halide w/ collimating adapter and light guide

Brightfield Illumination:

  • PRIOR Brightfield LED Illumination System LDB102NI

Stage:

  • Mechanical XY
  • Sutter Stage attachment

Micromanipulation:

  • Sutter MP-285 Micromanipulation
  • Sutter ROE285-2223 Micromanipulation Stage Controller

Amplification:

  • HEKA Patch Clamp EPC10 USB

Objectives:

  • 6-position Mechanical Turret
  • 4x/0.13 Plan Fluor
  • 10x/0.30 Plan Fluor DIC L/N1
  • 20x/0.75 Plan Apo VC (this is a high quality Nikon APO CFI60 Objective, it was originally installed in a custom piece of equipment where manufacturer did not want to show that they used Nikon objectives)

*Other objectives available - please inquire*
DIC Components/Polarization:

  • T-A2 Analyzer
  • T-P2 Polarizer
  • 10x DIC prism
  • 20x DIC prism

Photo/Port Splits:

  • 100% Eyepiece, 0% Camera
  • 20% Eyepiece, 80% Camera

Camera:

  • 10MP CMOS Camera

Computer and Software:

  • Computer running PatchMaster (v2x92) software w/dongle, and applicable camera software


Communication and power cables.

 

This configuration includes any 3 of these new filter sets.

  • New filter set - DAPI (EX: 365/28nm, DM: 405nm, EM: 445/50nm) (Dye compatibility: DAPI/Hoechst/AlexaFluor 350)
  • New filter set - EGFP/FITC/Cy2 (EX: 475/30nm, DM: 500nm, EM: 530/40nm) (Dye compatibility: EGFP/FITC/Cy2/AlexaFluor 488)
  • New filter set - TRITC/Cy3/Dsred (EX: 545/20nm, DM: 562nm, EM: 605/60nm) (Dye compatibility: TRITC/Cy3/RFP/Rhodamine/AlexaFluor 546)
  • New filter set - Texas Red (EX: 560/20nm, DM: 585nm, EM: 630/40nm) (Dye compatibility: Texas Red/mCherry/AlexaFluor 594)
  • New filter set - Cy5 (May require an upgraded light source) (EX: 630/50nm, DM: 662nm, EM: 695/50nm) (Dye compatibility: Cy5/AlexaFluor 647/Draq5)

 

This microscope's imaging capabilities:

Imaging software highlights:

  • Ability to take still images and live videos of your samples
  • Display, annotate, edit, calibrate, measure, analyze, process, print, and save raster
  • Variable linear measurements such as line segment, radius values, and others 

 

We can customize this microscope to fit your requirements:

 

  Add Microscopy Techniques (In addition to installed Brightfield, Fluorescence and DIC)

  • Phase Contrast

 

 Increase Maximum Magnification and Image Quality:

  • Microscope can be configured for magnification between 40x and 1000x (with 10x Eyepieces)
  • We can add standard higher magnification Nikon microscope objectives 
  • We can add high-end Nikon objectives

 

 Enhance fluorescence capabilities by adding/changing filters and upgrading light sources.

  • Additional filter cubes
  • Additional filter sets to match your fluorochromes.
  • Xenon, Metal Halide, or LED Fluorescence microscope light sources

 

We will also ensure the fluorescence light source matches your selected filter sets.

 

 Enhance imaging capabilities: 

  • We offer various advanced CCD, sCMOS, and EMCCD camera options for higher-quality images.

 

 We can configure it to work with the sample medium you need:

  • Slide, Petri dish, microplate, etc

 

 Commonly Requested Customer Upgrades

  • High-End CCD, sCMOS Cameras
  • LED or Metal Halide Fluorescence Light Sources
  • Phase Contrast, Polarization, or the DIC configurations
  • Higher Magnification Objectives
  • Higher performance Fluor or APO objectives
  • Motorized XY Stage (stage, controller, joystick)

 

We are excited to help build and configure the right microscope for you!

 

Nikon Ti-S Fluorescence Microscope Overview 

(Final microscope capabilities will depend on the modifications you request)

 

The fully manual Nikon Ti-U inverted microscope offers extensive capabilities for observing samples in various biological and materials science contexts. With manual control over objectives, focus, and illumination, it provides adaptable and precise sample examination. Users can easily adjust magnification levels for detailed exploration, manipulate focus for accuracy, and customize illumination sources to enhance contrast and visibility. Its inverted design facilitates the examination of thick samples or live specimens in containers such as petri dishes or culture flasks. This microscope caters to researchers and scientists who require hands-on control and flexibility in their microscopy experiments, facilitating detailed observation and analysis across a wide range of disciplines. The addition of phase contrast on an inverted microscope allows for clear visualization and detailed examination of transparent or unstained specimens, offering enhanced contrast and revealing intricate cellular structures with remarkable clarity.

 

The microscope is suitable for the following applications as configured:

  • Fluorescence microscopy: Ideal for fluorescent labeling and imaging of cells and tissues.
  • Material science research: Suitable for examining material properties and structures.
  • Biological research: Essential for cellular structure, function, and behavior studies.
  • Pharmacological studies: Facilitates the investigation of drug effects on cells and tissues.
  • Biotechnology applications: Enables genetic engineering and molecular biology research.
  • Educational purposes: Serves as a teaching tool in universities and research institutes.

 

Other potential applications:

  • Phase contrast and DIC: Enhances visibility of transparent specimens without staining.
  • High-resolution imaging: Provides clear, detailed images for in-depth analysis of samples.

 

Brochure: Nikon Ti-S Microscope Brochure


Manual: Nikon Ti-S Microscope Manual

 

Video Overview: 

 

Check out our microscopy capabilities:

 https://www.bostonind.com/our-microscopy-capabilities

 

 

 How we pack

 

Why do so many customers choose to order from us?

 

  • We make sure to match the microscope capabilities to your requirements.
  • We have experience servicing and repairing these microscopes.
  • This microscope goes through an extensive set of service steps before shipping.
  • We offer detailed photos and videos of the microscopes you buy.
  • We are an approved pre-owned equipment vendor to many large US, Canadian, and EU Universities.
  • We are an approved pre-owned equipment vendor to many Fortune 500 US and International Biopharma companies. 
  • Many upgrade and repair parts are in stock.
  • Remote installation and microscope operation training are available.
  • On-site installation may be available in the Boston Area (New England area)
  • Expert US or International shipping is available (see the shipping tab on how we pack and feel at ease)

 

  • Warranty
  • An extended warranty may be available.
  • You get after-sales technical support.
  • Customer references are available.
  • The microscope will be complete and working!
  • Smooth process from the initial quote to order fulfillment.


*SM* Small Crate
300#

 

COMMON CUSTOMER QUESTIONS AND ANSWERS BELOW

 

What steps do you take to verify, service, and confirm the functionality of the Nikon Electrophysiology Rig Patch Clamp Ti-S microscope?

We verify various microscope functions individually and together, performing necessary repairs or maintenance to bring the microscope to our quality standards.

 

  • We confirm the microscope's physical condition.
  • We meticulously inspect and clean the optical path within the microscope.
  • We lubricate mechanical components.
  • We assess light source quality using various fluorescence and non-fluorescence samples.
  • We ensure the stage moves smoothly in both fine and coarse adjustments.
  • We ensure the smooth operation of all mechanical parts.
  • We confirm that all electronic/motorized components are working well.
  • We set up communication between the microscope, installed components, and the software.
  • We test the camera by acquiring sample images.
  • We confirm the responsiveness of any included touchscreens and buttons.
  • We ensure necessary accessories and cables are included.

 

Electrophysiology specific testing:

  • Tested live feed for clarity: PASSED
  • Tested Sutter MP-285 MicroManipulator: PASSED
  • Tested HEKA EPC 10: PASSED
  • Verified live reading with software: PASSED
  • Perform "Full Test" function with PatchMaster software: PASSED

 

Can you help me identify the best microscope and configuration for me?

We are here to help.

  • Contact us with your application; we will help you identify the best microscope configuration.
  • We do not believe in a one-size-fits-all approach; you should get a microscope that will do what you need.

Can I view the Nikon Electrophysiology Rig Patch Clamp Ti-S microscope in person at your facility or do a live Zoom demo before it is shipped to me?

We invite you to visit our facility for an on-site demo, or feel free to request a virtual Zoom demo of the microscope you are interested in.

 

 What about the warranty? Installation, training, maintenance?

Warranty Terms:

  • The microscope is fully warranted for parts and labor.

 

The customer should retain all packing materials during the warranty period. 

 

Installation & Training:

 

Option 1 – In Person

If your lab is located within two hours of Boston, we may be able to offer in-person installation and training in person.

 

Option 2 – Remote/Virtual

Our remote training is conducted via Zoom, allowing us to significantly reduce its cost and offer it to customers outside our travel area.

 

Both training options include:

  • Review of the microscope and its capabilities.
  • Microscope and software operation.
  • Review of the recommended maintenance procedures.

 

 We generally recommend these training services to anyone who is new to this microscope model.

 

What should I watch out for when buying a Nikon Electrophysiology Rig Patch Clamp Ti-S microscope used/pre-owned from another lab?
  • Make sure the microscope is properly packed for shipping and will arrive safely. If the microscope has many components, request to have it packed in a wooden crate.
  • Confirm that there is no physical damage or any misaligned internal components. 
  • Ask what accessories are included.
  • Ask how long the warranty is and what it covers.

 

Here is what our technical team tests so you can request something similar and ensure your microscope will be fully functional.

  • We confirm the microscope's physical condition.
  • We meticulously inspect and clean the optical path within the microscope.
  • We assess light quality using various fluorescence and non-fluorescence samples.
  • We ensure the stage moves smoothly in both fine and coarse adjustments.
  • We ensure the smooth operation of all mechanical components.
  • We confirm that all electronic/motorized components are working well.
  • We set up communication between the microscope, installed components, and the software.
  • We test the camera by acquiring sample images.
  • We confirm the responsiveness of any included touchscreens and buttons.
  • We ensure necessary accessories and cables are included.

 

We recommend inspecting the microscope in person with your sample or requesting a virtual demo; this will allow you to evaluate the condition and performance of the microscope you are considering purchasing.

 

 Do you have a Nikon Electrophysiology Rig Patch Clamp Ti-S microscope on hand?
  • Yes, this is a common microscope model we carry, and we stock multiple accessories and many replacement parts to back up our warranty.

 

I found it elsewhere for less. What goes into your price?

We acknowledge that sometimes you can purchase this model microscope elsewhere, possibly for less.

 

Here are some of the reasons for our price.

  • Our microscope will be fully serviced.
  • It will be customized and configured to your requirements.
  • We may offer longer standard warranty terms.
  • We cover shipping costs during the warranty period. (Customer is required to save packing materials for the duration).
  • We have to employ technical staff that can do the testing/repairs and after-sales support if there are any issues.
  • We invest considerable time into the testing and service of each microscope we sell.
  • We have to purchase any missing required accessories to make the microscopes complete.
  • We have to procure and stock service parts to fulfill our warranty.
  • We have extensive experience packing sensitive instruments. See the shipping section in the website menu for info on how not to pack.
  • We guarantee that the microscope will be functional.

 

This procurement is for a University or College. Are purchase orders with NET terms accepted?
  • If you are a US or Canadian customer, we are likely already a registered vendor in your University's vendor system. This would greatly expedite the process of PO approvals and get this instrument into your lab faster.
  • POs are accepted from US and Canadian universities.

 

 How fast will you ship?
  • We can ship within a few days to 2 weeks, depending on your required microscope customization.

 

Will my microscope be insured during shipping?
  • All microscopes shipped within the USA and internationally are fully insured. This applies as long as we are the shipper and handle shipping arrangements.
  • If the buyer handles shipping, then shipping insurance responsibility falls to the buyer; we highly advise that the buyer obtain shipping insurance from their carrier.

 

 How do you pack? Have you previously packed and shipped a Nikon Electrophysiology Rig Patch Clamp Ti-S microscope? Do you ship Internationally?

Packing

  • Smaller microscopes ship via UPS Parcel Delivery with adequate packing material and a strong box. Or, when combined with other orders, it may be packed in a crate.
  • Most larger microscopes ship in fully enclosed ISPM15-certified wooden crates with proper padding underneath, and the sides have moving components braced.
  • Accessories are packed safely in boxes with padding and then safely packed inside the crate.
  • We may not use a crate for local deliveries to save you money *if delivered by us.
  • We often use “tilt’ & “shock” indicators on the crates to ensure the crate has not been excessively tilted and dropped where equipment may suffer damage.
  • Photos are taken during the packing process to make sure nothing is missed.

USA/Canada Shipping

  • Within the US and Canada, we will ship via selected freight carriers. We do not use low-price/high-damage carriers as we want the equipment to get safely to you.

International Shipping

  • Internationally, we will only ship via Air Freight or Air Parcel (such as UPS or DHL), which provides reliability, no exposure to Ocean weather, and timely delivery.
    We have extensive experience packing and shipping fragile microscopes globally.

Our experience and process

  • We have safely packed and shipped thousands of sensitive analytical instruments. 

 

How much will I save buying it pre-owned, and is it worth it?

A lot…and it is undoubtedly worth it, and here is why.  Feel free to ask for feedback from hundreds of customers who bought from us.

 

  • When compared to buying a new one, you will save up to 60% to 80% and have plenty of funds left over for an additional instrument or two.
  • You will get our standard warranty, plus, when available, an option to obtain an extended warranty agreement. 
  • Know that your microscope was tested and working the day it left our facility and is covered if there are faults.
 Sustainability
  • Well, this one is easy: buying a pre-owned microscope is great for the planet; you are reducing unnecessary waste, CO2 output, and water use that would be used during the manufacturing process.   

 

 I have more questions; I want to receive a formal quote.

Absolutely! Please give us a call (1-617-397-3486) or complete this form to get your questions answered or receive a formal Quote.

 

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Tags: Nikon Electrophysiology Rig DIC Fluorescence Microscope w/ Sutter Micromanipulator MP-285 , HEKA EPC 10 Patch Clamp , Faraday Cage , Inverted