Unchained Labs

Sample volume: 9 uL in sealed capillaries
Temp range: 15–95 DegC, ±0.1 DegC accuracy
Heating rate: 0.1–10 DegC/min
Size range: 0.3–1000 nm (DLS)
Wavelength range: 250–720 nm (fluorescence)

Up to 96 formulations produced within 6 hours
Total flow rate range of 0.1–30 mL/min (chip dependent)
Flow rate ratio from 1:1 to 5:1 with in-line dilution
Typical sample volumes from 400 µL to 2 mL
Delivers 40–200 nm particles with <0.2 PDI and >90% encapsulation

UV/Vis (230–750 nm) and 660 nm DLS detection with high spectral accuracy and sub-2 nm resolution
Protein, DNA, and particle sizing measurements from 2 µL samples using dual 0.1 mm/0.7 mm pathlengths
96-well plate capacity with ~10 min UV/Vis runs or ~1 hr combined UV/Vis + DLS analysis
Wide quantification range: dsDNA 1.5–13,750 ng/µL and protein 0.03–275 mg/mL
Absorbance precision to ±0.01 OD (10 mm) and particle size accuracy to ±2%

UV/Vis (230–750 nm) and 660 nm DLS detection with high spectral accuracy and sub-2 nm resolution
Protein, DNA, and particle sizing measurements from 2 µL samples using dual 0.1 mm/0.7 mm pathlengths
96-well plate capacity with ~10 min UV/Vis runs or ~1 hr combined UV/Vis + DLS analysis
Wide quantification range: dsDNA 1.5–13,750 ng/µL and protein 0.03–275 mg/mL
Absorbance precision to ±0.01 OD (10 mm) and particle size accuracy to ±2%

Light Source: Xenon flashlamp
Detectors: UV/Vis polychromatic spectrophotometer
Wavelength Range: 230-750nm; Wavelength Accuracy: =<0.2nm
Spectral Resolution: 2-2.5nm (FWHM at Hg 253.7nm)
Absorbance Precision: 0.001 OD (0.5mm path); Absorbance Accuracy: 4% (0.66 OD at 350nm)

Light Source: Xenon flashlamp
Detectors: UV/Vis polychromatic spectrophotometer
Wavelength Range: 230-750nm; Wavelength Accuracy: =<0.2nm
Spectral Resolution: 2-2.5nm (FWHM at Hg 253.7nm)
Capacity: 96-well