Most Microscopes ship within 3 to 10 business days Hundreds of Custom Microscopes Shipped | |
Customization available such as objectives, filter cubes, light sources, stages, cameras, and other components | |
Happy to provide references of past customers that bought microscopes from us | |
Save at least 60%+ vs. buying new and use those funds on another instrument instead. |
- Stock: In Stock
- Brand: Leica
- Product Code: SM100129-MG1MHXY
- Condition: Pre-Owned
For Sale Leica DM6000 Upright Fluorescence Microscope Pred Leica DM6
Configured with a motorized XY stage suitable for petri dishes and slides.
Can be setup with other motorized stages (microplate or multi-slide).
The Predecessor to Leica DM6 Upright Fluorescence Microscope
Condition, availability, and customization
- Fully functional, serviced, and in good condition
- Optics professionally cleaned
- *Comes with Brand New Fluorescence Filter Sets*
- Can be custom configured to the requirements of your application
- Will arrive timely, complete, and ready to be used
Leica DM6000 Fluorescence Microscope Overview
(Final microscope capabilities will depend on the modifications you request)
Grade:
- Research Grade Microscope
Microscopy types as configured:
- For Brightfield and Fluorescence Microscopy
Suited for the following applications as configured:
- High-quality imaging of live cells, tissues, microorganisms, and other
Installed automation/motorized components:
- Motorized lightpath
- Motorized/automated Z-Axis Drive
- Motorized filter cube turret
- Motorized objective(nosepiece) turret
Benefits of motorized/Automated Z-Axis drive:
- Automatic parfocality adjustment
- The ability to recall previously saved focus levels
- Automated management of Z positioning/ Fine-coarse control
Imaging of Samples:
- Ability to take still images and live videos of your samples
Imaging software highlights:
- Display, annotate, edit, calibrate, measure, analyze, process, print, and save raster
- Variable linear measurements such as line segment, radius values, and others
Open source Micromanager Multi-dimensional Image acquisition & automation software capabilities
- Multi-frame (Time lapse/Image acquisition over time)
- Multi-slice (Z coordinate/Z Stacking)
- *Multi-position (XY coordinate/Stitching/Mosaic) – only available when setup with motorized XY Stage
This is our Standard Leica DM6000 Fluorescence Microscope Configuration:
Microscope Base:
- Leica DM6000 upright Base
- with a Motorized(Automated) Z-Axis Drive
Microscope Head:
- Trinocular head with camera port
- Two Eyepieces
Fluorescence Light Path:
- Leica fluorescence motorized lightpath
Fluorescence Illumination:
- EXFO X-Cite 120 Metal Halide source
- Light Light Guide
- Collimating adapter
Fluorescence filter cube turret:
- Motorized 8-position filter cube turret
Fluorescence filters:
- Three empty filter cubes
- Three Brand New filter sets of either DAPI, FITC, Texas Red, or CY3
Brightfield Light Path:
- Built into microscope base
Brightfield Illumination:
- Leica 100 Watt halogen light source
- Leica 100 Watt halogen power supply
Objective Turret:
- Motorized 7-position objectives turret
Objectives:
4x/0.10 PL objective
10x/0.30 PL Fluotar objective
20x/0.50 PL Fluotar objective
Condenser:
- Mechanical condenser
Stage:
- Motorized XY Stage
- Controller
- Joystick
Stage Insert/Medium:
- As configured may be used with slides or Petri dishes
(Motorized XY stage will be as shown or similar, guranteed to work with your sample)
Camera ports:
- 100% Eyepiece, 0% Camera
- 20% Eyepiece, 80% Camera
- 0% Eyepiece, 100% Camera
Camera adapter:
- 1x C-mount adapter
Camera:
- CMOS USB 3.0 10MP Camera
Computer:
- Dell laptop computer
Software
- Windows 10
- Micromanager w/ImageJ Software
- Camera software
Accessories:
- Necessary power and communication cables
Modifications and Upgrades Available (thousands of components on hand, priced on average 55-75% off the original price)
Most customers do elect to have microscopes configured to their requirements.
Configurations (In addition to installed Brightfield, and Fluorescence)
- Phase Contrast, DIC, or Polarization Add-on Components may be added (subject to availability)
Maximum Magnification:
- Microscope can be configured for magnification between 40x and 1000x (with 10x Eyepieces)
- Higher magnification Leica microscope objectives
- Various high-end objectives (APO)
Fluorescence Capabilities:
New filter set - DAPI
(EX: 365/28nm, DM: 405nm, EM: 445/50nm)
(Dye compatibility: DAPI/Hoechst/AlexaFluor 350)
New filter set - EGFP/FITC/Cy2
(EX: 475/30nm, DM: 500nm, EM: 530/40nm)
(Dye compatibility: EGFP/FITC/Cy2/AlexaFluor 488)
New filter set - TRITC/Cy3/Dsred
(EX: 545/20nm, DM: 562nm, EM: 605/60nm)
(Dye compatibility: TRITC/Cy3/RFP/Rhodamine/AlexaFluor 546)
New filter set - Texas Red
(EX: 560/20nm, DM: 585nm, EM: 630/40nm)
(Dye compatibility: Texas Red/mCherry/AlexaFluor 594)
New filter set - Cy5 (May require an upgraded light source)
(EX: 630/50nm, DM: 662nm, EM: 695/50nm)
(Dye compatibility: Cy5/AlexaFluor 647/Draq5)
- Extra Filter cubes
- Xenon, Metal Halide, or LED Fluorescence microscope light sources
Imaging Capabilities:
- Various advanced CCD and sCMOS camera options for higher-quality images
Motorized/Automation Capabilities:
- In addition to installed motorized capabilities, it can be configured with:
- Motorized high-speed shutter, motorized condenser
Biological Samples:
- May be set up with other motorized XY stage kits for multi-slide scanning or full microplate scan
Happy to help build and configure the right microscope for you!
Most Requested Customer Upgrades
- High-End CCD, sCMOS, or EMCCD Camera
- LED Fluorescence Light Source
- Phase Contrast, Polarization, or the DIC configurations
- Higher Magnification Objectives
- Higher performance Fluor or APO objectives
- Motorized XY Stage Kit (stage, controller, joystick)
How to decide between a refurbished and brand-new comparable microscope
Will I save much by buying it pre-owned?
- Add many upgrades noted above
- Add a 1-Year Extended Warranty
- Add Setup and Training
- Get imaging capabilities comparable to Leica DM6 Microscope
- Get imaging quality comparable to Leica DM6 Microscope
- Get all upgrades from one place
- Still, save up to $60,000 vs buying new
Our Advantage
- We are passionate about microscopy!
- We offer detailed photos and video of the microscope in action
- Are an approved vendor to most large US and Canadian Universities & Colleges
- Are an approved vendor to many US and International Biopharma companies
- We carry hundreds of advanced research microscopes in stock
- Thousands of upgrade, modification, and repair parts in stock
- Remote installation and microscope operation training packages
- International shipping is no problem
Our Guarantee
- In Stock, Multiple Leica DM6000 Microscopes on hand if you require more than one
- The microscope comes with parts and a labor 90 Days Warranty
- An extended 1-year warranty option may be available with optional yearly renewal for North American customers
- Remote installation and training options
- Smooth process from the initial quote to custom order fulfillment
- Customer references at many universities
Brochure: Leica DM6000 Upright Fluorescence Motorized Microscope
Manual: Leica DM6000 Upright Fluorescence Motorized Microscope
COMMON QUESTIONS AND ANSWERS BELOW
Steps you take to verify, service, and confirm the functionality of the Leica DM6000 Fluorescence Microscope?
Summary of testing & maintenance we perform (depending on included configuration):
- Leica DM6000 upright Internal and external optics are inspected and cleaned
- Mechanical components inspected, adjusted, and lubricated if necessary
- The proper operation of electronic components is confirmed
- Any necessary repairs and services completed to make sure the microscope is fully functional
- Motorized components inspected for worn components, serviced and lubricated if necessary
- Objectives are inspected to ensure there is no inside dust and a clear image is produced
- Halogen lamp (if installed) we install a new Halogen bulb
- Fluorescence HBO Lamp (if installed) we install a new HBO bulb
- If the microscope has a Metal Halide Lamp source, we make sure the bulb has a minimum of 600 hours left on it
- We inspect image quality of fluorescence images by looking at various fluorescing slide samples
- Cameras are tested to ensure there is no condensation and they produce a clear image
- Camera image quality verified
Can you help me identify the best microscope and configuration for me?
We are here to help
- Contact us with your application; we will help you identify the best microscope configuration.
- We do not believe in one size fits all approach; you should get a microscope that will do what you need.
Can I view the microscope in person at your facility or do a live Zoom demo before it is shipped to me?
We offer both onsite and remote demos via Zoom
- We invite you to come in for an onsite or Zoom demo of the microscope
- On a custom configured microscopes, we generally offer a demo before the microscope is ready to ship out
What about the warranty?
Our Leica DM6000 upright Fluorescence microscopes come with a 90 Day Warranty.
Warranty Terms:
- The warranty term is 90 Days from the date of the microscope's arrival at the destination.
- This includes parts and labor.
- The customer should retain all packing materials during the warranty period.
Exceptions:
- The warranty does not cover bulbs except LED (LED lamps are covered)
- Damage to the objectives or other optical components due to collision with a sample (improper use)
- Electrical damage to the motorized/electronic components if the microscope plugged into an incorrect voltage
Do you offer installation, service, etc?
- We offer several remote installation and training packages.
- We offer an extended warranty agreement on this model.
- We stock various replacement and upgrade parts, so we may continue to support your microscope.
What should I watch out for when buying a Leica DM6000 Fluorescence Microscope used/pre-owned from another lab?
Basic steps to confirm quality:
- Confirm that internal optics are clean; this is often a complex undertaking, especially complex microscopes with motorized components.
- Confirm there is no present physical damage to the microscope base
- Confirm there are no cracked lenses inside the microscope light paths or the base
- Make sure there are no loose/damaged/seized gears inside mechanical and especially motorized components
- Make sure a good amount of life left on fluorescence sources and light guides (if present) are damage free
- If Microscope has a motorized stage, make sure it does not skip steps and moves freely on all axis
- Make sure objectives are installed, have been inspected, and have no damage or dust inside
- Confirm that microscope is configured to your application; any changes later will be expensive
- Confirm that camera is tested and communicates with the computer producing clear images
- Make sure there are no missing components; it won`t be fast or inexpensive to correct
If you have concerns, we highly recommend either inspecting the microscope in person or doing a live Zoom call; this will allow you to evaluate the microscope and confirm that everything works on it.
Do you have these and other microscopes on hand?
- Subject to ongoing demand, we usually stock 100 to 150 of ready to go fluorescence microscopes (preconfigured)
- Generally, we also have 150 to 200 microscopes in the process; those will be configured per the customer’s requirements.
- We specialize in microscopes from Leica, Zeiss, Nikon, and Olympus.
This procurement is for a University or College, are purchase orders with NET terms accepted?
- If you are a US or Canadian customer very likely we are already a registered and approved vendor in your University's vendor system(that is how many instruments we sold), this will simplify and expedite the process of PO approval.
- POs are accepted from US and Canadian universities.
How fast will you ship?
- We can ship within a few days to 2 weeks, depending on your required Leica DM6000 microscope customization.
Will my instrument be insured during shipping?
- All Leica DM6000 Fluorescence Microscopes are shipped fully insured within the US and internationally as long as we are a shipper and handle shipping arrangements.
- If the buyer handles shipping, then shipping insurance responsibility falls to the buyer; we highly advise that the buyer obtain shipping insurance from their carrier.
How do you pack? Have you packed and shipped microscopes in the past? Do you ship Internationally?
Packing
- Most microscopes ship in fully enclosed ISPM-15 certified wooden crates, with proper padding underneath and the sides, and have moving components braced.
- Accessories are packed safely in boxes with padding and then safely packed inside the crate.
- We may not use a crate for local deliveries or smaller microscopes to save you money *if delivered by us.
- On the crates, we often use “tilt’ & “shock” indicators to ensure the crate has not been excessively tilted and dropped where equipment may suffer damage.
- Photos are taken during the packing process to make sure nothing is missed
USA/Canada Shipping
- Within US and Canada, we will ship via selected freight carriers. We do not use low-price/high-damage carriers as we want the equipment to get safely to you.
International Shipping
- Internationally we will only ship via Air Freight or Air Parcel, which provides reliability, no exposure to Ocean weather, and timely delivery.
We have extensive experience shipping microscopes around the world.
Our experience and process
- We have safely packed and shipped hundreds of complex customized microscopes.
- Before packing/shipping, the instrument is re-tested, and a procedure is followed to verify the accuracy of included components.
How much will I save by buying it pre-owned, and is it worth it?
A lot…and it is certainly worth it, and here is why. Feel free to ask for feedback from hundreds of customers that bought custom microscopes from us.
- You will save around 60-80% vs. buying a new microscope. Spend leftover funds on another instrument for your lab.
- You will get a 90 days warranty, plus, when available, an option to get an extended warranty agreement.
- Many customers choose to invest funds into higher-end cameras that may not otherwise be considered due to cost at new prices.
- Consider getting a motorized stage, often a $10,000 to $20,000 upgrade, when bought new. Often save over 70% on the stage alone.
- For many applications, the difference in image quality between the current Leica DM6 microscope and this DM6000 may not make a major difference; instead, get better objectives or camera and have image quality exceed your expectations.
- You can have Leica DM6000 upright microscope configured to provide excellent viewing/imaging quality for a fraction of the cost
Leica DM6000 Upright Fluorescence Microscope is a predecessor model to the Leica DM6 Fluorescence microscope; DM6 could be priced up to $95,000. So why not save your funds by buying Leica DM6000, get the high-quality image quality you expect from Leica, and use your leftover funds elsewhere?
Sustainability
- Well, this one is easy; buying a pre-owned Leica DM6000 Microscope is great for the planet; you are reducing unnecessary waste, CO2 output, and water use that would be used during the manufacturing process.
I have more questions; I want to receive a formal quote.
Absolutely! Please give us a call (1-617-366-2699) or complete this form to get your questions answered or receive a formal Quote.
Examples of past Leica DM6000 Microscopes that we built
Customer: Hvidovre Hospital, Denmark Customer Application: This customer was looking for a fully motorized fluorescence imaging microscope to view their cancer research. The Leica DM6000 is a modular microscope system, that allows customization and flexibility to meet the specific needs of cancer research.
Customer Requested Modifications:
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Customer: Weill Cornell Medicine, New York
The customer was looking for a way to scan a single slide for fluorescence immunology samples and requested phase contrast options. Fluorescence microscopy enables the detection and analysis of immune responses, including immune cell interactions, antibody labeling, and cytokine expression within tissues.
Customer Requested Modifications:
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Customer: International Independent Researcher
This customer was looking for a reasonably priced time-lapse slide-imaging microscope for biological studies with DIC options for Pharmacological research. The Leica DM6000 microscope provides valuable functionality and performance for pharmacology and drug discovery research. It empowers researchers to visualize, analyze, and understand the effects of drugs on cellular processes, contributing to the development of new therapeutics and advancements in pharmacological science.
Customer Requested Modifications:
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Customer: Research Facility in Shanghai China This customer was looking for a budget-friendly motorized microscope for viewing cells for neurological research. In neuroscience, fluorescence microscopy helps researchers visualize neuronal structures, track neural activity, study synaptic connections, and investigate the mechanisms underlying neurological disorders.
Customer Requested Modifications:
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Customer: Baylor University, Texas
This customer requested a fully motorized microscope that could be used for studying the development of organisms by visualizing morphological changes, tracking cell migration, and examining gene expression patterns during embryogenesis.
Customer Requested Modifications:
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Customer: Doyle Lab, Arizona
This customer wanted an upright microscope for viewing samples at very high magnification in molecular biological studies. The Leica DM6000 microscope provides researchers in molecular biology with the necessary tools and performance to investigate molecular interactions, cellular processes, and molecular mechanisms. It aids in advancing our understanding of gene expression, molecular signaling pathways, and molecular interactions, contributing to the field of molecular biology.
Customer Requested Modifications:
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Freight Microscope Packaging Process
At our company we take packing and shipping very seriously.
No one wants to spend thousands of dollars and receive a damaged instrument.
Our process involves evaluating every microscope and its components to determine the safest positioning and structure for packing.
Most of our microscopes will ship in an ISPM-15 wood crate made from ½” plywood and 1x4 framing. (Crates are Internationally Compliant).
During microscope packing we often disconnect any protruding components like lamp housings, sliders, eyepieces, light guides.
We provide easy reassembly instructions to reinstall such components.
Components and accessories not installed on the microscope are bubble wrapped and packed in individual boxes.
Any remaining space inside the crates is filled with bubble wrap to prevent any movement and provide for additional cushion.
All of our crates ship with carrier instructions “Do Not Stack“ and include visual customer reminders to inspect the shipment on arrival.
Crates are also marked with instructions to retain packaging material until the instrument is inspected/verified and warranty period passed.
Parcel Microscope Packaging Process
Same as with freight shipments we take packing and shipping very seriously.
No one wants to spend thousands of dollars and receive a damaged instrument.
Our process includes evaluating every microscope and its components to determine the best shipment and packing method.
Microscopes that are small enough to ship via parcel (UPS/FEDEX) are often taken apart with all components safely wrapped with bubble wrap.
Safety of shipment is a number one priority so we may often pack microscopes into multiple boxes to assure safe delivery.
Boxes have a foam bottom liner and are filled with bubble wrap to prevent any movement of content inside during transit to your location.