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Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6

Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6
Leica DM6000 Upright Fluorescence Motorized Microscope with Motorized XY Stage Pred DM6

Approved Vendor to many US, Canada, and EU Universities

US & International Shipping

Hundreds of Custom Microscopes  Shipped
Customer References Available 
Training and Installation Options Available

 

  • Stock: In Stock
  • Brand: Leica
  • Product Code: SM100129-MG1MHXY
  • Condition: Pre-Owned
$9,995.00
CLICKABLE TABS BELOW

For Sale Leica DM6000 Upright Fluorescence Microscope with Motorized XY Stage Pred Leica DM6

 

  • Fully Functional
  • Serviced & in Stock
  •  Customized to your requirements
  •  Technical sales consultation available
  •  Continental USA 180 DAYS WARRANTY & 60 DAYS INTERNATIONAL
  •  Includes remote microscope training session and software overview
  • More info about our Microscopy Capabilities or view the Microscope Buying Guide

 

The Predecessor to the Leica DM6 Upright Fluorescence Microscope


 

This is what you will receive before customizing this microscope:

Standard Leica DM6000 Microscope Configuration: 

 

Microscopy Techniques:

Brightfield and Fluorescence Microscopy

 

Microscope Base:

  • Leica DM6000 upright Base
  • with a Motorized(Automated) Z-Axis Drive

Microscope Head:

  • Trinocular head with camera port
  • Two Eyepieces

Fluorescence Light Path:

  • Leica fluorescence motorized lightpath

Fluorescence Illumination:

  • EXFO X-Cite 120 Metal Halide source
  • Light Light Guide
  • Collimating adapter

Fluorescence filter cube turret:

  • Motorized 5-position filter cube turret

Fluorescence filters:

  • Three filter cubes

Brightfield Light Path:

  • Built into microscope base

Brightfield Illumination:

  • Leica 100 Watt halogen light source
  • Leica 100 Watt halogen power supply

Objective Turret:

  • Motorized 6-position objectives turret

Objectives:

  • 4x/0.10 PL objective
  • 10x/0.30 PL Fluotar objective
  • 20x/0.50 PL Fluotar objective

Condenser:

  • Mechanical condenser

Stage:

  • Motorized XY Stage
  • Controller
  • Joystick

Camera ports:

  • 100% Eyepiece, 0% Camera
  • 20% Eyepiece, 80% Camera
  • 0% Eyepiece, 100% Camera

Camera adapter:

  • 1x C-mount adapter 

Camera:

  • CMOS USB 3.0 10MP Camera

Computer & Software:

  • Dell laptop computer with Windows 10
  • Micromanager w/ImageJ analysis software
  • Camera software

Accessories:

  • Necessary power and communication cables

 

Automated/motorized capabilities of this microscope:

Installed automation/motorized components:

  • Motorized lightpath
  • Motorized/automated Z-Axis Drive
  • Motorized filter cube turret
  • Motorized objective(nosepiece) turret
  • Motorized XY Stage

 

 Benefits of motorized/Automated Z-Axis drive:

  • Automatic parfocality adjustment
  • The ability to recall previously saved focus levels
  • Automated management of Z positioning/ Fine-coarse control

 

This microscope's imaging capabilities:

Imaging software highlights:

  • Ability to take still images and live videos of your samples
  • Display, annotate, edit, calibrate, measure, analyze, process, print, and save raster
  • Variable linear measurements such as line segment, radius values, and others 
  • Open source Micromanager Multi-dimensional Image acquisition & automation software capabilities
  • Multi-frame (Time lapse/Image acquisition over time) 
  • Multi-slice (Z coordinate/Z Stacking)  
  • Multi-position (XY coordinate/Stitching/Mosaic) – only available when equipped with a motorized XY Stage.

 

We can customize this microscope to fit your requirements:

 

  Add Microscopy Techniques (In addition to installed Brightfield and Fluorescence)

  • Phase Contrast, DIC, or Polarization Add-on Components may be added (subject to availability)

 

 Increase Maximum Magnification and Image Quality:

  • Microscope can be configured for magnification between 40x and 1000x (with 10x Eyepieces)
  • We can add standard higher magnification Leica microscope objectives 
  • We can add high-end Leica objectives

 

 Enhance fluorescence capabilities by adding/changing filters and upgrading light sources.

  • Additional filter cubes
  • Additional filter sets to match your fluorochromes.
  • Xenon, Metal Halide, or LED Fluorescence microscope light sources

 

We will also ensure the fluorescence light source matches your selected filter sets.

 

 Enhance imaging capabilities: 

  • We offer various advanced CCD, sCMOS, and EMCCD camera options for higher-quality images.

 

  Add other Motorized/Automation Capabilities: 

    In addition to installed motorized capabilities, the microscope can be configured

  • Motorized high-speed shutter

 

 We can configure it to work with the sample medium you need:

  • Slide, Petri dish, microplate, etc
  • It may also be set up with a motorized XY stage for multi-slide or full microplate scans.

 

 Commonly Requested Customer Upgrades

  • High-End CCD, sCMOS Cameras
  • LED or Metal Halide Fluorescence Light Sources
  • Phase Contrast, Polarization, or the DIC configurations
  • Higher Magnification Objectives
  • Higher performance Fluor or APO objectives
  • Motorized XY Stage (stage, controller, joystick)

 

We are excited to help build and configure the right microscope for you!

 

Leica DM6000 Fluorescence Microscope Overview 

(Final microscope capabilities will depend on the modifications you request)

 

The Leica DM6000 is an advanced upright microscope tailored for researchers and clinicians requiring exceptional imaging capabilities. Equipped with a motorized Z-Axis drive, objective turret, and a motorized fluorescence filter cube turret alongside a motorized stage compatible with standard slide holders, this microscope ensures seamless magnification switching, fluorescence imaging versatility, and precise specimen manipulation. Its superior optics and intuitive interface facilitate detailed visualization of cellular structures and dynamic biological processes across diverse applications such as cell biology, neuroscience, and pathology. 

 

Leica DM6000 is suitable for the following applications as configured:

  • Fluorescence microscopy: Ideal for fluorescent labeling and imaging of cells and tissues.
  • Material science research: Suitable for examining material properties and structures.
  • Biological research: Essential for cellular structure, function, and behavior studies.
  • Pharmacological studies: Facilitates the investigation of drug effects on cells and tissues.
  • Biotechnology applications: Enables genetic engineering and molecular biology research.
  • Educational purposes: Serves as a teaching tool in universities and research institutes.
  • Time-lapse photography: Captures sequential images to monitor changes over time.
  • Multi-dimensional imaging: Allows for the acquisition of images in multiple planes and dimensions.
  • Quantitative analysis: Supports measurements and quantification of specimen features.

 

Other potential applications:

  • Phase contrast and DIC: Enhances visibility of transparent specimens without staining.
  • High-resolution imaging: Provides clear, detailed images for in-depth analysis of samples.

 

Brochure: Leica DM6000 Upright Fluorescence Motorized Microscope

Manual: Leica DM6000 Upright Fluorescence Motorized Microscope

 

Video Overview: 

 

Check out our microscopy capabilities:

 https://www.bostonind.com/our-microscopy-capabilities

 

 

 How we pack

 


Why do so many customers choose to order from us?

 

  • We make sure to match the microscope capabilities to your requirements.
  • We have experience servicing and repairing these microscopes.
  • This microscope goes through an extensive set of service steps before shipping.
  • We offer detailed photos and videos of the microscopes you buy.
  • We are an approved pre-owned equipment vendor to many large US, Canadian, and EU Universities.
  • We are an approved pre-owned equipment vendor to many Fortune 500 US and International Biopharma companies. 
  • Many upgrade and repair parts are in stock.
  • Remote installation and microscope operation training are available.
  • On-site installation may be available in the Boston Area (New England area)
  • Expert US or International shipping is available (see the shipping tab on how we pack and feel at ease)

 

  • Warranty
  • An extended warranty may be available.
  • You get after-sales technical support.
  • Customer references are available.
  • The microscope will be complete and working!
  • Smooth process from the initial quote to order fulfillment.


*SM* Small Crate
200#


 

COMMON CUSTOMER QUESTIONS AND ANSWERS BELOW

 

What steps do you take to verify, service, and confirm the functionality of the Leica DM6000 microscope?

We verify various microscope functions individually and together, performing necessary repairs or maintenance to bring the microscope to our quality standards.

 

  • We confirm the microscope's physical condition.
  • We meticulously inspect and clean the optical path within the microscope.
  • We lubricate mechanical components.
  • We assess light source quality using various fluorescence and non-fluorescence samples.
  • We ensure the stage moves smoothly in both fine and coarse adjustments.
  • We ensure the smooth operation of all mechanical parts.
  • We confirm that all electronic/motorized components are working well.
  • We set up communication between the microscope, installed components, and the software.
  • We test the camera by acquiring sample images.
  • We confirm the responsiveness of any included touchscreens and buttons.
  • We ensure necessary accessories and cables are included.

 

Can you help me identify the best microscope and configuration for me?

We are here to help.

  • Contact us with your application; we will help you identify the best microscope configuration.
  • We do not believe in a one-size-fits-all approach; you should get a microscope that will do what you need.

Can I view the Leica DM6000 microscope in person at your facility or do a live Zoom demo before it is shipped to me?

We invite you to visit our facility for an on-site demo, or feel free to request a virtual Zoom demo of the microscope you are interested in.

 

 What about the warranty? Installation, training, maintenance?

Warranty Terms:

  • The microscope is fully warranted for parts and labor.

 

The customer should retain all packing materials during the warranty period. 

 

Installation & Training:

 

Option 1 – In Person

If your lab is located within two hours of Boston, we may be able to offer in-person installation and training in person.

 

Option 2 – Remote/Virtual

Our remote training is conducted via Zoom, allowing us to significantly reduce its cost and offer it to customers outside our travel area.

 

Both training options include:

  • Review of the microscope and its capabilities.
  • Microscope and software operation.
  • Review of the recommended maintenance procedures.

 

 We generally recommend these training services to anyone who is new to this microscope model.

 

What should I watch out for when buying a Leica DM6000 microscope used/pre-owned from another lab?
  • Make sure the microscope is properly packed for shipping and will arrive safely. If the microscope has many components, request to have it packed in a wooden crate.
  • Confirm that there is no physical damage or any misaligned internal components. 
  • Ask what accessories are included.
  • Ask how long the warranty is and what it covers.

 

Here is what our technical team tests so you can request something similar and ensure your microscope will be fully functional.

  • We confirm the microscope's physical condition.
  • We meticulously inspect and clean the optical path within the microscope.
  • We assess light quality using various fluorescence and non-fluorescence samples.
  • We ensure the stage moves smoothly in both fine and coarse adjustments.
  • We ensure the smooth operation of all mechanical components.
  • We confirm that all electronic/motorized components are working well.
  • We set up communication between the microscope, installed components, and the software.
  • We test the camera by acquiring sample images.
  • We confirm the responsiveness of any included touchscreens and buttons.
  • We ensure necessary accessories and cables are included.

 

We recommend inspecting the microscope in person with your sample or requesting a virtual demo; this will allow you to evaluate the condition and performance of the microscope you are considering purchasing.

 

 Do you have a Leica DM6000 microscope on hand?
  • Yes, this is a common microscope model we carry, and we stock multiple accessories and many replacement parts to back up our warranty.

 

I found it elsewhere for less. What goes into your price?

We acknowledge that sometimes you can purchase this model microscope elsewhere, possibly for less.

 

Here are some of the reasons for our price.

  • Our microscope will be fully serviced.
  • It will be customized and configured to your requirements.
  • We may offer longer standard warranty terms.
  • We cover shipping costs during the warranty period. (Customer is required to save packing materials for the duration).
  • We have to employ technical staff who can do the testing/repairs and provide after-sales support if there are any issues.
  • We invest considerable time into the testing and service of each microscope we sell.
  • We have to purchase any required accessories that are missing to complete the microscopes.
  • We have to procure and stock service parts to fulfill our warranty.
  • We have extensive experience packing sensitive instruments. See the shipping section in the website menu for info on how not to pack.
  • We guarantee that the microscope will be functional.

 

This procurement is for a University or College. Are purchase orders with NET terms accepted?
  • If you are a US or Canadian customer, we are likely already a registered vendor in your University's vendor system. This would greatly expedite the process of PO approvals and get this instrument into your lab faster.
  • POs are accepted from US and Canadian universities.

 

 How fast will you ship?
  • We can ship within a few days to 2 weeks, depending on your required microscope customization.

 

Will my microscope be insured during shipping?
  • All microscopes shipped within the USA and internationally are fully insured. This applies as long as we are the shipper and handle shipping arrangements.
  • If the buyer handles shipping, then shipping insurance responsibility falls to the buyer; we highly advise that the buyer obtain shipping insurance from their carrier.

 

 How do you pack? Have you previously packed and shipped a Leica DM6000 microscope? Do you ship Internationally?

Packing

  • Smaller microscopes ship via UPS Parcel Delivery with adequate packing material and a strong box. Or, when combined with other orders, it may be packed in a crate.
  • Most larger microscopes ship in fully enclosed ISPM15-certified wooden crates with proper padding underneath, and the sides have moving components braced.
  • Accessories are packed safely in boxes with padding and then safely packed inside the crate.
  • We may not use a crate for local deliveries to save you money *if delivered by us.
  • We often use “tilt’ & “shock” indicators on the crates to ensure the crate has not been excessively tilted and dropped where equipment may suffer damage.
  • Photos are taken during the packing process to make sure nothing is missed.

USA/Canada Shipping

  • Within the US and Canada, we will ship via selected freight carriers. We do not use low-price/high-damage carriers as we want the equipment to get safely to you.

International Shipping

  • Internationally, we will only ship via Air Freight or Air Parcel (such as UPS or DHL), which provides reliability, no exposure to Ocean weather, and timely delivery.
    We have extensive experience packing and shipping fragile microscopes globally.

Our experience and process

  • We have safely packed and shipped thousands of sensitive analytical instruments. 

 

How much will I save buying it pre-owned, and is it worth it?

A lot…and it is undoubtedly worth it, and here is why.  Feel free to ask for feedback from hundreds of customers who bought from us.

 

  • When compared to buying a new one, you will save up to 60% to 80% and have plenty of funds left over for an additional instrument or two.
  • You will get our standard warranty, plus, when available, an option to obtain an extended warranty agreement. 
  • Know that your microscope was tested and working the day it left our facility and is covered if there are faults.
 Sustainability
  • Well, this one is easy: buying a pre-owned microscope is great for the planet; you are reducing unnecessary waste, CO2 output, and water use that would be used during the manufacturing process.   

 

 I have more questions; I want to receive a formal quote.

Absolutely! Please give us a call (1-617-397-3486) or complete this form to get your questions answered or receive a formal Quote.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Examples of past Leica DM6000 Microscopes that we built

 

  

Customer: Hvidovre Hospital, Denmark

SKU-32263

 

Customer Application: 

This customer was looking for a fully motorized fluorescence imaging microscope to view their cancer research. The Leica DM6000 is a modular microscope system, that allows customization and flexibility to meet the specific needs of cancer research.

 

Customer Requested Modifications:

  • From a full spectrum metal halide fluorescence source to a multi-band LED light source. LED light sources emit less heat and negligible amounts of UV or infrared radiation, minimizing phototoxic effects on live cancer cells during imaging. This is especially advantageous for long-term imaging studies or investigations involving sensitive cellular processes or drug response evaluations.
  • From our default DAPI, FITC, Texas Red filter sets to Attenuated DAPI, FITC, Texas Red, and CY3 filters. The Leica DM6000 can be equipped with fluorescence modules, such as fluorescence filter sets and fluorescence illuminators, allowing for precise fluorescence imaging and analysis of cancer cells and fluorescently tagged biomarkers.
  • The total magnification range of this microscope with 10x eyepieces and installed objectives was increased to 400x. The Leica DM6000 is known for its exceptional optical performance, providing high-resolution and contrast imaging. Its high-quality lenses and optics ensure clear visualization of cellular structures, which is crucial for studying cancer cells and their characteristics.
  • The stage was swapped from a manual XY stage to a motorized stage. A precise and stable stage with fine focus adjustment allows for accurate positioning and focusing of the slide containing cancer cells.
  • In combination with the base’s motorized Z focus, the new stage allowed for imaging options like Z stacking with mosaic stitching. The Leica DM6000 offers imaging automation capabilities, such as motorized stages, autofocus systems, and advanced software, enabling efficient and precise imaging of multiple samples, time-lapse experiments, and image analysis workflows.

Customer: Weill Cornell Medicine, New York

SKU-25856


Customer Application: 

The customer was looking for a way to scan a single slide for fluorescence immunology samples and requested phase contrast options. Fluorescence microscopy enables the detection and analysis of immune responses, including immune cell interactions, antibody labeling, and cytokine expression within tissues.

 

Customer Requested Modifications:

  • From our default, DAPI, FITC, Texas Red filter sets to FITC, Texas Red, and CY3 filtersImmunology often involves the use of fluorescent labeling to visualize specific immune cells, antibodies, or molecular markers. The Leica DM6000 can be equipped with fluorescence modules and filter sets, allowing precise and high-quality fluorescence imaging for immunological studies. 
  • Phase contrast annuals and matching objectives were added to allow for contrast imaging. Immunology studies often require visualization of cellular morphology and structural details. The Leica DM6000 supports various contrast techniques, including brightfield, phase contrast, and differential interference contrast (DIC), enabling researchers to observe immune cells and their interactions with enhanced contrast and detail. 
  • The total magnification range of this microscope with 10x eyepieces and installed objectives was increased to 630x. The Leica DM6000 delivers exceptional optical performance, including high-resolution imaging capabilities. This is critical for immunology research, as it allows researchers to observe and analyze fine details of immune cells, subcellular structures, or cellular interactions.
  • The CMOS camera was upgraded to a CCD which delivers exceptional optical performance, including high-resolution imaging. This is critical for immunology research, as it allows researchers to observe and analyze fine details of immune cells, subcellular structures, or cellular interactions.
  • The new stage allowed for full slide scanning using image capture and processing software. These automation capabilities enhance workflow efficiency and enable high-throughput imaging and data acquisition.  

Customer: International Independent Researcher

SKU-24565


Customer Application: 

This customer was looking for a reasonably priced time-lapse slide-imaging microscope for biological studies with DIC options for Pharmacological research. The Leica DM6000 microscope provides valuable functionality and performance for pharmacology and drug discovery research. It empowers researchers to visualize, analyze, and understand the effects of drugs on cellular processes, contributing to the development of new therapeutics and advancements in pharmacological science.

 

Customer Requested Modifications:

  • From our default, DAPI, FITC, Texas Red filter sets to DAPI, FITC, Texas Red, and CY3 filters. Pharmacology and drug discovery often involve the use of fluorescent probes, dyes, or markers to study drug-target interactions, cellular responses, and drug efficacy. The Leica DM6000 can be equipped with fluorescence modules and filter sets, enabling precise and high-quality fluorescence imaging for pharmacological studies. 
  • Differential Interference Contrast prisms and matching objectives were added to allow for contrast imaging. The Leica DM6000 supports various contrast techniques, such as brightfield, phase contrast, and differential interference contrast (DIC). These techniques facilitate the observation of cellular morphology, structural changes, and drug-induced alterations, enhancing the visualization of cellular responses to pharmacological treatments. 
  • The total magnification range of this microscope with 10x eyepieces and installed objectives was increased to 400x. The Leica DM6000 delivers exceptional optical performance, providing high-resolution imaging capabilities. This is crucial in pharmacology and drug discovery research to observe and analyze cellular structures, drug uptake, intracellular localization, and drug-target interactions at a microscopic level.
  • The stage was swapped from a manual XY stage to a motorized stage. Pharmacological studies often require imaging multiple samples or conducting high-throughput experiments. The Leica DM6000 features motorized stage and imaging automation capabilities, enabling efficient and precise sample positioning, multi-site imaging, and time-lapse experiments. Automation reduces human error and enhances workflow efficiency.
  • The head was swapped for a more ergonomic model. Prolonged microscope use is common in pharmacology research. The Leica DM6000 is designed with ergonomic considerations, such as adjustable eyepieces, comfortable stage controls, and customizable settings, ensuring user comfort during extended periods of observation, analysis, and experimentation. 

Customer: Research Facility in Shanghai China 

SKU-30483
Customer Application: 

This customer was looking for a budget-friendly motorized microscope for viewing cells for neurological research. In neuroscience, fluorescence microscopy helps researchers visualize neuronal structures, track neural activity, study synaptic connections, and investigate the mechanisms underlying neurological disorders.

 

Customer Requested Modifications:

  • Our default DAPI, FITC, and Texas Red filter sets were changed to Texas Red, CY3, and CY5. Neurological studies often require the simultaneous imaging of multiple fluorophores or fluorescent labels to investigate complex neuronal processes or multiple molecular targets. The Leica DM6000 supports multi-channel imaging, allowing researchers to capture and analyze multiple fluorescent signals within a single sample.
  • The total magnification range of this microscope with 10x eyepieces and installed objectives was increased to 630x. The Leica DM6000 provides excellent optical performance, including high-resolution imaging capabilities. This is crucial in neurology research to observe and analyze fine details of neuronal structures, synaptic connections, and cellular morphology.
  • The addition of Micromanager and FIJI software allowed for quantitative analysis of neuronal structures, such as dendritic spine density, axonal length, or neuronal connectivity. The Leica DM6000 combined with imaging software for automated image analysis, data quantification, and statistical analysis, facilitating accurate and efficient data processing.
  • The stage was swapped from a manual XY stage to a motorized stage. The Leica DM6000 offers imaging automation features, including motorized stages, which are valuable for high-throughput imaging, multi-site imaging, and time-lapse experiments in neurology research. Automation enhances workflow efficiency and allows for precise and reproducible imaging.
  • The new stage allowed for joystick control which allowed for quick scanning of their samples during viewing. Neurology research can involve long hours of microscope use. The Leica DM6000 is designed with ergonomic considerations, such as adjustable eyepieces, comfortable stage controls, and customizable settings, ensuring user comfort during extended periods of observation and analysis.

Customer: Baylor University, Texas

SKU-26413


Customer Application: 

This customer requested a fully motorized microscope that could be used for studying the development of organisms by visualizing morphological changes, tracking cell migration, and examining gene expression patterns during embryogenesis.

 

Customer Requested Modifications: 

  • From our default, DAPI, FITC, Texas Red filter sets to DAPI, FITC, Texas Red, and CY3 filters. Developmental biology often involves the use of fluorescent markers or dyes to visualize specific developmental processes, gene expression patterns, or cell lineage tracing. The Leica DM6000 can be equipped with fluorescence modules and filter sets, enabling precise and high-quality fluorescence imaging for studying cellular dynamics and molecular interactions during development. 
  • The total magnification range of this microscope with 10x eyepieces and installed objectives was increased to 400x. The Leica DM6000 provides exceptional optical performance, including high-resolution imaging capabilities. This is crucial in developmental biology to observe and analyze fine details of embryonic structures, tissue morphogenesis, and cellular differentiation during various stages of development.
  • The stage was swapped from a manual XY stage to a motorized stage. The Leica DM6000 offers imaging automation features, including motorized stages and autofocus systems, which are valuable for high-throughput imaging, time-lapse experiments, and multi-site imaging in developmental biology research. Automation enhances workflow efficiency and allows for precise and reproducible imaging.
  • The new stage allowed for a full slide scanning function to be added to time-lapse image capture. Utilizing Micromanager and FIJI software, quantitative analysis of developmental structures, such as cell counts, tissue measurements, or growth dynamics is possible. The Leica DM6000 combined with imaging software for automated image analysis, data quantification, and statistical analysis, facilitating accurate and efficient data processing.

Customer: Doyle Lab, Arizona 

SKU-15307


Customer Application: 

This customer wanted an upright microscope for viewing samples at very high magnification in molecular biological studies. The Leica DM6000 microscope provides researchers in molecular biology with the necessary tools and performance to investigate molecular interactions, cellular processes, and molecular mechanisms. It aids in advancing our understanding of gene expression, molecular signaling pathways, and molecular interactions, contributing to the field of molecular biology. 

 

Customer Requested Modifications:

  • From our default, DAPI, FITC, Texas Red filter sets to DAPI, Texas Red, and CY3 filters. Molecular biology often involves the use of fluorescent probes, dyes, or markers to visualize specific molecules, gene expression patterns, or cellular events. The Leica DM6000 can be equipped with fluorescence modules and filter sets, enabling precise and high-quality fluorescence imaging for studying molecular interactions, protein localization, and cellular processes. 
  • The total magnification range of this microscope with 10x eyepieces and installed objectives was increased to 1000x. The Leica DM6000 provides exceptional optical performance, including high-resolution imaging capabilities. This is crucial in molecular biology to visualize and analyze subcellular structures, cellular processes, and molecular interactions at a microscopic level.
  • APO objectives were selected for their superior imaging capabilities.APO objectives are designed to minimize chromatic aberration, which is the phenomenon that causes different colors of light to focus at slightly different points. This reduction in chromatic aberration improves image quality by enhancing color accuracy, contrast, and resolution. It allows for clearer and more precise imaging of samples, especially when using multiple wavelengths or fluorescence imaging.
  • The stage was swapped from a manual XY stage to a motorized stage. The Leica DM6000 offers imaging automation features, including motorized stages and autofocus systems, which are valuable for high-throughput imaging, time-lapse experiments, and multi-site imaging in molecular biology research. Automation enhances workflow efficiency and allows for precise and reproducible imaging. The new stage allowed for the still placement of the samples during oil immersion image capture
  • The addition of Micromanager and FIJI software allows for quantitative analysis of molecular structures, protein expression levels, or cellular dynamics. The Leica DM6000 can be combined with imaging software for automated image analysis, data quantification, and statistical analysis, facilitating accurate and efficient data processing.

 

Freight Microscope Packaging Process

At our company we take packing and shipping very seriously.
No one wants to spend thousands of dollars and receive a damaged instrument.

Our process involves evaluating every microscope and its components to determine the safest positioning and structure for packing.
Most of our microscopes will ship in an ISPM-15 wood crate made from ½” plywood and 1x4 framing. (Crates are Internationally Compliant).

During microscope packing we often disconnect any protruding components like lamp housings, sliders, eyepieces, light guides.
We provide easy reassembly instructions to reinstall such components.

Components and accessories not installed on the microscope are bubble wrapped and packed in individual boxes.
Any remaining space inside the crates is filled with bubble wrap to prevent any movement and provide for additional cushion.

All of our crates ship with carrier instructions “Do Not Stack“ and include visual customer reminders to inspect the shipment on arrival.
Crates are also marked with instructions to retain packaging material until the instrument is inspected/verified and warranty period passed.

 







 

Parcel Microscope Packaging Process

Same as with freight shipments we take packing and shipping very seriously.
No one wants to spend thousands of dollars and receive a damaged instrument.

Our process includes evaluating every microscope and its components to determine the best shipment and packing method.

Microscopes that are small enough to ship via parcel (UPS/FEDEX) are often taken apart with all components safely wrapped with bubble wrap.
Safety of shipment is a number one priority so we may often pack microscopes into multiple boxes to assure safe delivery.

Boxes have a foam bottom liner and are filled with bubble wrap to prevent any movement of content inside during transit to your location.